Global Patent Index - EP 0687472 A3

EP 0687472 A3 19970115 - Potentiation of drug response by a serotonin 1A receptor antagonist

Title (en)

Potentiation of drug response by a serotonin 1A receptor antagonist

Title (de)

Potenzierung von Wirkstoffresponz durch Serotonin 1A Rezeptor Antagonisten

Title (fr)

Potentialisation d'un médicament par un antagoniste du récepteur sérotonine 1A

Publication

EP 0687472 A3 19970115 (EN)

Application

EP 94307876 A 19941026

Priority

  • US 26085794 A 19940616
  • US 27746094 A 19940719

Abstract (en)

[origin: EP0687472A2] The power of fluoxetine, venlafaxine, milnacipran and duloxetine to increase the availability of serotonin, norepinephrine and dopamine, particularly serotonin, is augmented by administration in combination with a drug which is a serotonin 1A receptor antagonist.

IPC 1-7

A61K 45/06

IPC 8 full level

A61K 31/445 (2006.01); A61K 31/13 (2006.01); A61K 31/135 (2006.01); A61K 31/138 (2006.01); A61K 31/38 (2006.01); A61K 31/395 (2006.01); A61K 31/40 (2006.01); A61K 31/41 (2006.01); A61K 31/435 (2006.01); A61K 31/475 (2006.01); A61K 31/495 (2006.01); A61K 31/535 (2006.01); A61K 31/54 (2006.01); A61K 31/55 (2006.01); A61K 45/06 (2006.01); A61P 9/12 (2006.01)

CPC (source: EP US)

A61K 31/135 (2013.01 - EP US); A61K 31/38 (2013.01 - EP US); A61K 31/40 (2013.01 - EP US); A61K 45/06 (2013.01 - EP US); A61P 9/12 (2017.12 - EP)

C-Set (source: EP US)

  1. A61K 31/40 + A61K 31/38
  2. A61K 31/40 + A61K 31/135
  3. A61K 31/38 + A61K 31/135
  4. A61K 31/135 + A61K 31/135
  5. A61K 31/135 + A61K 2300/00
  6. A61K 31/38 + A61K 2300/00
  7. A61K 31/40 + A61K 2300/00

Citation (search report)

  • [X] HJORTH, AUERBACH: "further evidence for the importance of 5HT1A autoreceptors in the action of selective serotonin reuptake inhibitors", EUROPEAN JOURNAL OF PHARMACOLOGY, vol. 260, 1994, pages 251 - 255, XP000605645
  • [X] R.W. FULLER ET AL: "EFFECT OF FLUOXETINE PRETREATMENT ON THE NEUROCHEMICAL CHANGES INDUCED BY AMFONELIC ACID COMBINED WITH SPIPERONE IN RATS", JOURNAL OF PHARMACY AND PHARMACOLOGY, vol. 38, no. 10, 1986, pages 776 - 777, XP000607084
  • [X] SIMON ET AL: "5-HT1A RECEPTOR BLOCKADE INCREASES PENILE ERECTIONS INDUCED BY INDIRECT SEROTONIN AGONISTS", NEUROREPORT, vol. 5, no. 3, 1993, pages 229 - 230, XP000607249
  • [X] MENESES, HONG: "EFFECT OF FLUOXETINE ON LEARNING AND MEMORY INVOLVES MULTIPLE 5-HT SYSTEMS", PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR, vol. 52, no. 2, 1995, pages 341 - 346, XP000607087
  • [A] ARTIGAS ET AL: "PINDOLOL INDUCES A RAPID IMPROVEMENT OF DEPRESSED PATIENTS TREATED WITH SEROTONIN REUPTAKE INHIBITOR", ARCHIVES OF GENERAL PSYCHIATRY, vol. 51, no. 3, 1994, pages 248 - 251, XP000605678

Designated contracting state (EPC)

AT BE CH DE DK ES FR GB GR IE IT LI LU NL PT SE

DOCDB simple family (publication)

EP 0687472 A2 19951220; EP 0687472 A3 19970115; AU 685510 B2 19980122; AU 7742194 A 19960104; CA 2134038 A1 19951217; CA 2134038 C 19970603; CN 1113436 A 19951220; CO 4340731 A1 19960730; CZ 262494 A3 19960117; HU 9403071 D0 19941228; HU T71582 A 19951228; IL 111380 A0 19941229; JP H083035 A 19960109; NO 944046 D0 19941024; NO 944046 L 19951218; NZ 264774 A 19970727; PE 28695 A1 19951004; PL 305701 A1 19951227; SG 70562 A1 20000222; US 5532244 A 19960702; US 5532250 A 19960702; US 5532264 A 19960702; US 5532268 A 19960702; US 5538992 A 19960723; US 5552429 A 19960903

DOCDB simple family (application)

EP 94307876 A 19941026; AU 7742194 A 19941024; CA 2134038 A 19941021; CN 94119338 A 19941027; CO 94049618 A 19941031; CZ 262494 A 19941024; HU 9403071 A 19941024; IL 11138094 A 19941024; JP 28493394 A 19941118; NO 944046 A 19941024; NZ 26477494 A 19941025; PE 25399194 A 19941102; PL 30570194 A 19941104; SG 1996008007 A 19941026; US 44260995 A 19950517; US 44273395 A 19950517; US 44273495 A 19950517; US 44273595 A 19950517; US 44273695 A 19950517; US 44273795 A 19950517