EP 0687472 A3 19970115 - Potentiation of drug response by a serotonin 1A receptor antagonist
Title (en)
Potentiation of drug response by a serotonin 1A receptor antagonist
Title (de)
Potenzierung von Wirkstoffresponz durch Serotonin 1A Rezeptor Antagonisten
Title (fr)
Potentialisation d'un médicament par un antagoniste du récepteur sérotonine 1A
Publication
Application
Priority
- US 26085794 A 19940616
- US 27746094 A 19940719
Abstract (en)
[origin: EP0687472A2] The power of fluoxetine, venlafaxine, milnacipran and duloxetine to increase the availability of serotonin, norepinephrine and dopamine, particularly serotonin, is augmented by administration in combination with a drug which is a serotonin 1A receptor antagonist.
IPC 1-7
IPC 8 full level
A61K 31/13 (2006.01); A61K 31/135 (2006.01); A61K 31/138 (2006.01); A61K 31/38 (2006.01); A61K 31/395 (2006.01); A61K 31/40 (2006.01); A61K 31/41 (2006.01); A61K 31/435 (2006.01); A61K 31/445 (2006.01); A61K 31/475 (2006.01); A61K 31/495 (2006.01); A61K 31/535 (2006.01); A61K 31/54 (2006.01); A61K 31/55 (2006.01); A61K 45/06 (2006.01); A61P 9/12 (2006.01)
CPC (source: EP US)
A61K 31/135 (2013.01 - EP US); A61K 31/38 (2013.01 - EP US); A61K 31/40 (2013.01 - EP US); A61K 45/06 (2013.01 - EP US); A61P 9/12 (2017.12 - EP)
Citation (search report)
- [X] HJORTH, AUERBACH: "further evidence for the importance of 5HT1A autoreceptors in the action of selective serotonin reuptake inhibitors", EUROPEAN JOURNAL OF PHARMACOLOGY, vol. 260, 1994, pages 251 - 255, XP000605645
- [X] R.W. FULLER ET AL: "EFFECT OF FLUOXETINE PRETREATMENT ON THE NEUROCHEMICAL CHANGES INDUCED BY AMFONELIC ACID COMBINED WITH SPIPERONE IN RATS", JOURNAL OF PHARMACY AND PHARMACOLOGY, vol. 38, no. 10, 1986, pages 776 - 777, XP000607084
- [X] SIMON ET AL: "5-HT1A RECEPTOR BLOCKADE INCREASES PENILE ERECTIONS INDUCED BY INDIRECT SEROTONIN AGONISTS", NEUROREPORT, vol. 5, no. 3, 1993, pages 229 - 230, XP000607249
- [X] MENESES, HONG: "EFFECT OF FLUOXETINE ON LEARNING AND MEMORY INVOLVES MULTIPLE 5-HT SYSTEMS", PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR, vol. 52, no. 2, 1995, pages 341 - 346, XP000607087
- [A] ARTIGAS ET AL: "PINDOLOL INDUCES A RAPID IMPROVEMENT OF DEPRESSED PATIENTS TREATED WITH SEROTONIN REUPTAKE INHIBITOR", ARCHIVES OF GENERAL PSYCHIATRY, vol. 51, no. 3, 1994, pages 248 - 251, XP000605678
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IE IT LI LU NL PT SE
DOCDB simple family (publication)
EP 0687472 A2 19951220; EP 0687472 A3 19970115; AU 685510 B2 19980122; AU 7742194 A 19960104; CA 2134038 A1 19951217; CA 2134038 C 19970603; CN 1113436 A 19951220; CO 4340731 A1 19960730; CZ 262494 A3 19960117; HU 9403071 D0 19941228; HU T71582 A 19951228; IL 111380 A0 19941229; JP H083035 A 19960109; NO 944046 D0 19941024; NO 944046 L 19951218; NZ 264774 A 19970727; PE 28695 A1 19951004; PL 305701 A1 19951227; SG 70562 A1 20000222; US 5532244 A 19960702; US 5532250 A 19960702; US 5532264 A 19960702; US 5532268 A 19960702; US 5538992 A 19960723; US 5552429 A 19960903
DOCDB simple family (application)
EP 94307876 A 19941026; AU 7742194 A 19941024; CA 2134038 A 19941021; CN 94119338 A 19941027; CO 94049618 A 19941031; CZ 262494 A 19941024; HU 9403071 A 19941024; IL 11138094 A 19941024; JP 28493394 A 19941118; NO 944046 A 19941024; NZ 26477494 A 19941025; PE 25399194 A 19941102; PL 30570194 A 19941104; SG 1996008007 A 19941026; US 44260995 A 19950517; US 44273395 A 19950517; US 44273495 A 19950517; US 44273595 A 19950517; US 44273695 A 19950517; US 44273795 A 19950517