EP 0689605 A1 19960103 - HEPATITIS B ESCAPE MUTANT SPECIFIC BINDING MOLECULES
Title (en)
HEPATITIS B ESCAPE MUTANT SPECIFIC BINDING MOLECULES
Title (de)
MOLEKULE, DIE EINE AUSBRUCHS-MUTANTE VON HEPATITIS B SPEZIFISCH BINDEN
Title (fr)
MOLECULES DE LIAISON SPECIFIQUES AUX MUTANTS LIBERES PAR L'HEPATITE B
Publication
Application
Priority
- GB 9400609 W 19940324
- GB 9306087 A 19930324
- GB 9311526 A 19930604
Abstract (en)
[origin: WO9421812A2] Molecules which are capable of specifically binding to a hepatitis B escape mutant antigenic determinant include monoclonal antibodies secreted by the cell line SMH HBs 145/G/R/I (ECACC 92122312), SMH HBs 145/R/I (ECACC 93052626), SMH HBs 145/G/R/II (ECACC 93033109) or SMH HBs 145/R/II (ECACC 93033110) and other specific binding molecules cross-competitive with them. Antibodies secreted by the cell lines SMH HBs 145/G/R/I and SMH HBs 145/G/R/II bind variant (escape mutant) HBsAG and wild type HBsAG. Antibodies secreted by the cell lines SMH HBs 145/R/I and SMH HBs 145/R/II bind variant but not wild type.
IPC 1-7
IPC 8 full level
G01N 33/576 (2006.01); A61K 39/395 (2006.01); A61P 31/12 (2006.01); C07K 16/08 (2006.01); C07K 16/10 (2006.01); C12N 5/10 (2006.01); C12N 15/02 (2006.01); C12P 21/08 (2006.01); G01N 33/577 (2006.01)
CPC (source: EP)
A61P 31/12 (2017.12); C07K 16/082 (2013.01)
Citation (search report)
See references of WO 9421812A2
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9421812 A2 19940929; WO 9421812 A3 19941110; AU 6287094 A 19941011; AU 681636 B2 19970904; CA 2158866 A1 19940929; CN 1121357 A 19960424; EP 0689605 A1 19960103; JP H08510635 A 19961112; NO 953749 D0 19950922; NO 953749 L 19951122; NZ 262929 A 19970822; PL 310699 A1 19951227
DOCDB simple family (application)
GB 9400609 W 19940324; AU 6287094 A 19940324; CA 2158866 A 19940324; CN 94191829 A 19940324; EP 94910464 A 19940324; JP 51150794 A 19940324; NO 953749 A 19950922; NZ 26292994 A 19940324; PL 31069994 A 19940324