EP 0690716 A1 19960110 - OLIGONUCLEOTIDES MODIFIED TO IMPROVE STABILITY AT ACID pH
Title (en)
OLIGONUCLEOTIDES MODIFIED TO IMPROVE STABILITY AT ACID pH
Title (de)
MODIFIZIERTE OLIGONUKLEOTIDE ZUR VERBESSERUNG DER STABILITÄT IM SAUREM PH-BEREICH
Title (fr)
OLIGONUCLEOTIDES MODIFIES POUR AMELIORER LA STABILITE A pH ACIDE
Publication
Application
Priority
- US 9400157 W 19940105
- US 110993 A 19930106
Abstract (en)
[origin: WO9415619A1] Acid resistant oligonucleotides modified by alkylation at the 2'-O-position are suitable for oral administration. Orally acceptable formulations prepared with the disclosed modified oligonucleotides as active ingredients are also provided.
IPC 1-7
IPC 8 full level
C07H 21/04 (2006.01); A61K 31/70 (2006.01); A61P 31/12 (2006.01); A61P 35/00 (2006.01); C07H 21/00 (2006.01)
CPC (source: EP KR)
A61K 31/70 (2013.01 - EP KR); A61P 31/12 (2017.12 - EP); A61P 35/00 (2017.12 - EP); C07H 21/00 (2013.01 - EP); C07H 21/02 (2013.01 - KR)
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9415619 A1 19940721; AU 5992494 A 19940815; AU 692143 B2 19980604; CA 2152672 A1 19940721; CN 1118140 A 19960306; EP 0690716 A1 19960110; EP 0690716 A4 19970502; IL 108206 A0 19940412; JP H08505396 A 19960611; KR 960700062 A 19960119; NZ 261253 A 19970727
DOCDB simple family (application)
US 9400157 W 19940105; AU 5992494 A 19940105; CA 2152672 A 19940105; CN 94191223 A 19940105; EP 94906041 A 19940105; IL 10820693 A 19931228; JP 51618894 A 19940105; KR 19950702783 A 19950706; NZ 26125394 A 19940105