EP 0691981 A1 19960117 - TUMOR TARGETING WITH L-ENANTIOMERIC OLIGONUCLEOTIDE CONJUGATES OF IMMUNOREAGENTS AND OF CHELATED RADIONUCLIDES
Title (en)
TUMOR TARGETING WITH L-ENANTIOMERIC OLIGONUCLEOTIDE CONJUGATES OF IMMUNOREAGENTS AND OF CHELATED RADIONUCLIDES
Title (de)
AUF TUMOR ZIELENDE L-ENANTIOMERE OLIGONUCLEOTIDKONJUGATE AUS IMMUNREAGENTIEN UND RADIONUCLIDCHELATEN
Title (fr)
CIBLAGE DE TUMEUR AU MOYEN DE CONJUGUES OLIGONUCLEOTIDIQUES L-ENANTIOMERES D'IMMUNOREACTIFS ET DE RADIONUCLEIDES CHELATES
Publication
Application
Priority
- US 9402610 W 19940310
- US 3308393 A 19930310
Abstract (en)
[origin: WO9420523A1] The present invention is directed to a non-radioactive targeting immunoreagent that comprises an immunoreactive group, one or more non-self-associating L-enantiomeric oligonucleotide sequences, and one or more linking groups, and to a radioactive targeting immunoreagent that comprises an L-enantiomeric oligonucleotide sequence that is complementary in sequence to and capable of hybridization with one or more fragments of a non-self-associating L-enantiomeric oligonucleotide sequence, one or more chelating agents, one or more linking groups, and one or more radionuclides. The present invention is also directed to pharmaceutical compositions comprising one or more of the above-described immunoreagents and a pharmaceutically acceptable carrier. The present invention is further directed to methods for treating and imaging disease sites in patients.
IPC 1-7
IPC 8 full level
A61K 39/395 (2006.01); A61K 51/00 (2006.01); A61K 51/10 (2006.01); C07H 21/00 (2006.01); C07K 16/00 (2006.01); G01N 33/574 (2006.01)
CPC (source: EP)
A61K 51/1093 (2013.01); C07H 21/00 (2013.01); A61K 2121/00 (2013.01); A61K 2123/00 (2013.01)
Citation (search report)
See references of WO 9420523A1
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9420523 A1 19940915; AU 6402594 A 19940926; CA 2157902 A1 19940915; EP 0691981 A1 19960117; JP H08512019 A 19961217
DOCDB simple family (application)
US 9402610 W 19940310; AU 6402594 A 19940310; CA 2157902 A 19940310; EP 94911542 A 19940310; JP 52031394 A 19940310