EP 0691987 A1 19960117 - CYCLIC COMPOUNDS USEFUL AS INHIBITORS OF PLATELET GLYCOPROTEIN IIb/IIIa
Title (en)
CYCLIC COMPOUNDS USEFUL AS INHIBITORS OF PLATELET GLYCOPROTEIN IIb/IIIa
Title (de)
ZYKLISCHE VERBINDUNGEN ALS INHIBITOREN DES PLATELET-GLYKOPROTEINS IIB/IIIA
Title (fr)
COMPOSES CYCLIQUES INHIBITEURS DE LA GLYCOPROTEINE PLAQUETTAIRE IIb/IIIa
Publication
Application
Priority
- US 9403223 W 19940328
- US 3844893 A 19930329
Abstract (en)
[origin: WO9422910A1] This invention relates to novel cyclic compounds containing carbocyclic ring systems useful as antagonists of the platelet glycoprotein IIb/IIIa complex, to pharmaceutical compositions containing such cyclic compounds, with or without other therapeutic agents, and to methods of using these compounds, with or without other therapeutic agents, for the inhibition of platelet aggregation, as thrombolytics, and/or for the treatment of other thromboembolic disorders. This invention also relates to methods of using the cyclic compounds of the invention in combination with anti-coagulants such as warfarin or heparin, or additional anti-platelet agents such as aspirin, piroxicam or ticlopidine, or thrombin inhibitors such as boropeptides, hirudin or argatroban, or thrombolytic agents such as tissue plasminogen activator, anistreplase, urokinase or streptokinase, or combinations thereof, for the treatment of thromboembolic disorders.
IPC 1-7
IPC 8 full level
A61K 31/135 (2006.01); A61K 31/35 (2006.01); A61K 31/405 (2006.01); A61K 31/54 (2006.01); A61K 31/60 (2006.01); A61K 38/00 (2006.01); A61K 38/46 (2006.01); A61K 38/55 (2006.01); A61P 7/02 (2006.01); C07K 5/12 (2006.01); C07K 7/54 (2006.01); C07K 14/75 (2006.01)
CPC (source: EP)
A61P 7/02 (2017.12); C07K 14/75 (2013.01); A61K 38/00 (2013.01)
Citation (search report)
See references of WO 9422910A1
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9422910 A1 19941013; AU 6415894 A 19941024; CA 2159070 A1 19941013; EP 0691987 A1 19960117; FI 954556 A0 19950926; FI 954556 A 19950926; HU 9502832 D0 19951128; HU T72896 A 19960628; JP H08508498 A 19960910; NO 953832 D0 19950928; NO 953832 L 19951128; NZ 263456 A 19961126; PL 310896 A1 19960108
DOCDB simple family (application)
US 9403223 W 19940328; AU 6415894 A 19940328; CA 2159070 A 19940328; EP 94911703 A 19940328; FI 954556 A 19950926; HU 9502832 A 19940328; JP 52219594 A 19940328; NO 953832 A 19950928; NZ 26345694 A 19940328; PL 31089694 A 19940328