Global Patent Index - EP 0694081 A4

EP 0694081 A4 19980715 - RECOMBINANT -g(a)-N-ACETYLGALACTOSAMINIDASE ENZYME AND cDNA ENCODING SAID ENZYME

Title (en)

RECOMBINANT -g(a)-N-ACETYLGALACTOSAMINIDASE ENZYME AND cDNA ENCODING SAID ENZYME

Title (de)

REKOMBINANTE -g(a)-N-ACETYLGALACTOSAMINIDASE UND c DNA KODIEREND FÜR DIESES ENZYM

Title (fr)

-g(a)-N-ACETYLGALACTOSAMINIDASE RECOMBINEE ET ADNc CODANT CETTE ENZYME

Publication

EP 0694081 A4 19980715 (EN)

Application

EP 94911730 A 19940328

Priority

  • US 9403338 W 19940328
  • US 3724893 A 19930326

Abstract (en)

[origin: WO9423070A1] This invention relates to a recombinant enzyme for use in the removal of A antigens from the surface of cells in blood products. Specifically, this invention is directed to a recombinant alpha -N-acetylgalactosaminidase enzyme from chicken liver, methods of cloning and expressing said recombinant alpha -N-acetylgalactosaminidase enzyme and a method of removing A antigens from the surface of cells in blood products using said recombinant alpha -N-acetylgalactosaminidase enzyme.

IPC 1-7

C12S 3/22; C12N 9/40; C12N 15/10; C12N 15/56; C12N 15/63; A01N 1/02

IPC 8 full level

A61K 35/18 (2006.01); C12N 1/19 (2006.01); C12N 1/21 (2006.01); C12N 9/24 (2006.01); C12N 9/40 (2006.01); C12N 15/09 (2006.01); C12N 15/56 (2006.01); C12S 3/22 (2006.01); C12R 1/19 (2006.01); C12R 1/865 (2006.01)

CPC (source: EP)

A61K 35/18 (2013.01); C12N 9/2402 (2013.01); C12Y 302/01049 (2013.01)

Citation (search report)

  • [E] WO 9409121 A1 19940428 - NEW YORK BLOOD CENTER INC [US]
  • [E] WO 9411518 A2 19940526 - GENENCOR INT [US]
  • [E] WO 9412628 A1 19940609 - SINAI SCHOOL MEDICINE [US]
  • [Y] J. HATA ET AL.: "Purification and characterization of N-acetyl-alpha-D-galactosaminidase from Gallus domesticus", BIOCHEMISTRY INTERNATIONAL, vol. 28, no. 1, October 1992 (1992-10-01), pages 77 - 86, XP002055397
  • [A] HOGAN, EDWARD L. ET AL: "Membrane glycosphingolipids in chicken muscular dystrophy", ADV. EXP. MED. BIOL. (1982), 152, 273-8 CODEN: AEMBAP;ISSN: 0065-2598, 1982, XP002055398
  • See references of WO 9423070A1

Designated contracting state (EPC)

AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE

DOCDB simple family (publication)

WO 9423070 A1 19941013; AU 6417594 A 19941024; AU 688310 B2 19980312; CA 2159083 A1 19941013; CA 2159083 C 20020702; EP 0694081 A1 19960131; EP 0694081 A4 19980715; JP H08508406 A 19960910

DOCDB simple family (application)

US 9403338 W 19940328; AU 6417594 A 19940328; CA 2159083 A 19940328; EP 94911730 A 19940328; JP 52225494 A 19940328