Global Patent Index - EP 0696199 A4

EP 0696199 A4 19970625 - AMIDINO AND GUANIDINO SUBSTITUTED BORONIC ACID INHIBITORS OF TRYPSIN-LIKE ENZYMES

Title (en)

AMIDINO AND GUANIDINO SUBSTITUTED BORONIC ACID INHIBITORS OF TRYPSIN-LIKE ENZYMES

Title (de)

MIT AMIDINO-UBD GUANIDINOGRUPPEN SUBSTITUIERTE BORONSAEURE ALS INHIBITOREN FUER TRYPSINAEHNLICHE ENZYME

Title (fr)

ACIDE BORONIQUE A SUBSTITUTION AMIDINO ET GUANIDINO EN TANT QU'INHIBITEUR D'ENZYMES DE TYPE TRYPSINE

Publication

EP 0696199 A4 19970625 (EN)

Application

EP 94914776 A 19940421

Priority

  • US 9404058 W 19940421
  • US 5283593 A 19930427
  • US 20405594 A 19940302

Abstract (en)

[origin: WO9425049A1] This invention relates to Novel alpha -aminoboronic acid and corresponding peptide analogs of formula (I) are disclosed.

IPC 1-7

A61K 38/00

IPC 8 full level

A61K 38/00 (2006.01); A61P 1/00 (2006.01); A61P 7/02 (2006.01); A61P 9/08 (2006.01); A61P 9/10 (2006.01); A61P 29/00 (2006.01); A61P 43/00 (2006.01); C07D 207/16 (2006.01); C07F 5/02 (2006.01); C07K 5/06 (2006.01); C07K 5/065 (2006.01); C07K 5/078 (2006.01); C07K 5/087 (2006.01); C07K 7/02 (2006.01); C07K 7/06 (2006.01); C07K 7/08 (2006.01)

CPC (source: EP)

A61P 1/00 (2017.12); A61P 7/02 (2017.12); A61P 9/08 (2017.12); A61P 9/10 (2017.12); A61P 29/00 (2017.12); A61P 43/00 (2017.12); C07D 207/16 (2013.01); C07F 5/025 (2013.01); C07K 5/06165 (2013.01); C07K 5/06191 (2013.01); C07K 5/0812 (2013.01); C07K 7/02 (2013.01); C07K 7/08 (2013.01); A61K 38/00 (2013.01)

Citation (search report)

  • [DX] WO 9207869 A1 19920514 - THROMBOSIS RES INST [GB]
  • [E] WO 9509634 A1 19950413 - DU PONT MERCK PHARMA [US]
  • [X] CLAESON, G. ET AL.: "Novel peptide mimetics as highly efficient inhibitors of thrombin based on D-Phe-Pro-Arg sequences", PEPT.: CHEM. BIOL., PROC. AM. PEPT. SYMP. 12TH, 1992, pages 824 - 825, XP000609384
  • [X] ELGENDY, S. ET AL.: "New peptide boronic acid inhibitors of thrombin", TETRAHEDRON LETTERS, vol. 33, no. 29, 1992, pages 4209 - 4212, XP000609104
  • [A] MATTESON, D.S. & SADHU, K.M.: "(R)-1-acetamido-2-phenylethaneboronic acid. ...", J. AM. CHEM. SOC., vol. 103, 1981, pages 5241 - 5242, XP002019969
  • See references of WO 9425049A1

Designated contracting state (EPC)

AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE

DOCDB simple family (publication)

WO 9425049 A1 19941110; AU 6703894 A 19941121; CA 2161216 A1 19941110; EP 0696199 A1 19960214; EP 0696199 A4 19970625; IL 109319 A0 19940731; JP H08509723 A 19961015; TW 286318 B 19960921

DOCDB simple family (application)

US 9404058 W 19940421; AU 6703894 A 19940421; CA 2161216 A 19940421; EP 94914776 A 19940421; IL 10931994 A 19940413; JP 52431694 A 19940421; TW 83104198 A 19940507