EP 0696272 A1 19960214 - CYCLOOXYGENASE AND 5-LIPOXYGENASE INHIBITING N(3-BIPHENYLYL-1(S)-METHYL-2-PROPENYL) ACETOHYDROXAMIC ACID DERIVATIVES
Title (en)
CYCLOOXYGENASE AND 5-LIPOXYGENASE INHIBITING N(3-BIPHENYLYL-1(S)-METHYL-2-PROPENYL) ACETOHYDROXAMIC ACID DERIVATIVES
Title (de)
CYCLOOXYGENASE UND 5-LIPOXYGENASE HEMMENDE N¬3-BIPHENYLYL-1(5)-METHYL-2-PROPENYL ACETOHYDROXAMSÄURE-DERIVATE
Title (fr)
DERIVES DE L'ACIDE ACETOHYDROXAMIQUE N (3-BIPHENYLYL-1(S)-METHYL-2-PROPENYL) INHIBITEURS DE LA CYCLOOXYGENASE ET DE LA 5-LIPOXYGENASE
Publication
Application
Priority
- GB 9308652 A 19930427
- GB 9318432 A 19930906
- GB 9400886 W 19940426
Abstract (en)
[origin: WO9425431A1] The present invention is concerned with novel hydroxamic acid derivatives of formula (I) and their use in medical therapy, particularly in the prophylaxis or treatment of clinical conditions for which an inhibitor of the lipoxygenase or cyclooxygenase mediated arachidonic acid metabolic pathway is indicated. The invention also relates to pharmaceutical formulations and processes for the preparation of compounds according to the invention. In formula (I), X is cyano, fluoro, or chloro; or a salt, solvate, or physiologically functional derivative thereof.
IPC 1-7
C07C 259/06; C07C 275/64; A61K 31/16; A61K 31/17; C07C 239/10; C07C 239/22; C07C 255/56; C07C 255/53; C07C 255/64; C07C 49/235; C07C 33/30
IPC 8 full level
A61K 31/165 (2006.01); A61K 31/275 (2006.01); A61P 1/00 (2006.01); A61P 1/04 (2006.01); A61P 11/00 (2006.01); A61P 43/00 (2006.01); C07C 17/263 (2006.01); C07C 33/28 (2006.01); C07C 33/48 (2006.01); C07C 45/00 (2006.01); C07C 45/72 (2006.01); C07C 49/235 (2006.01); C07C 239/10 (2006.01); C07C 239/18 (2006.01); C07C 255/53 (2006.01); C07C 255/56 (2006.01); C07C 255/60 (2006.01); C07C 259/06 (2006.01); C07C 271/00 (2006.01); C07C 271/08 (2006.01); C07C 275/64 (2006.01)
CPC (source: EP)
A61P 1/00 (2017.12); A61P 1/04 (2017.12); A61P 11/00 (2017.12); A61P 43/00 (2017.12); C07C 17/263 (2013.01); C07C 33/28 (2013.01); C07C 45/00 (2013.01); C07C 45/72 (2013.01); C07C 49/235 (2013.01); C07C 255/53 (2013.01); C07C 255/56 (2013.01); C07C 259/06 (2013.01); C07C 271/00 (2013.01); C07C 275/64 (2013.01)
Citation (search report)
See references of WO 9425431A1
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9425431 A1 19941110; AP 454 A 19960119; AP 9400637 A0 19940430; AU 6575094 A 19941121; CA 2161544 A1 19941110; EP 0696272 A1 19960214; HU 9501810 D0 19950828; HU T71556 A 19951228; IL 109430 A0 19940731; JP H08509718 A 19961015; TW 269679 B 19960201
DOCDB simple family (application)
GB 9400886 W 19940426; AP 9400637 A 19940426; AU 6575094 A 19940426; CA 2161544 A 19940426; EP 94913700 A 19940426; HU 9501810 A 19940426; IL 10943094 A 19940426; JP 52401994 A 19940426; TW 83103703 A 19940426