EP 0701560 A1 19960320 - BICYCLIC ETHER DERIVATIVES AND THEIR USE AS 5-LIPOXYGENASE INHIBITORS
Title (en)
BICYCLIC ETHER DERIVATIVES AND THEIR USE AS 5-LIPOXYGENASE INHIBITORS
Title (de)
BIZYKLISCHE ETHERDERIVATE UND IHRE VERWENDUNG ALS 5-LIPOXYGENASEINHIBITOREN
Title (fr)
DERIVES D'ETHER BICYCLIQUES ET LEUR UTILISATION COMME INHIBITEURS DE LA 5-LIPOXYGENASE
Publication
Application
Priority
- EP 94919601 A 19940603
- EP 9401805 W 19940603
- EP 93401407 A 19930602
Abstract (en)
[origin: WO9427999A1] The invention concerns a bicyclic ether derivative of formula (I), wherein Ar<1> is phenyl or naphthyl, or a 10-membered bicyclic heterocyclic moiety containing one or two nitrogen heteroatoms and optionally containing a further heteroatom selected from nitrogen, oxygen and sulphur; A is a direct link to the group X or A is (1-4C)alkylene; X is oxy, thio, sulphinyl or sulphonyl; Ar<2> is phenylene, pyridinediyl, pyrimidinediyl, thiophendiyl, furandiyl or thiazolediyl; and R<1> is (1-4C)alkyl, (3-4C)alkenyl or (3-4C)alkynyl; or a pharmaceutically-acceptable salt thereof; processes for their preparation; pharmaceutical compositions containing them and their use as 5-lipoxygenase inhibitors.
IPC 1-7
IPC 8 full level
C07D 493/08 (2006.01); A61K 31/35 (2006.01); A61P 43/00 (2006.01); C07D 495/08 (2006.01)
CPC (source: EP)
A61P 43/00 (2017.12); C07D 495/08 (2013.01)
Citation (search report)
See references of WO 9427999A1
Designated contracting state (EPC)
CH DE ES FR GB IT LI
DOCDB simple family (publication)
WO 9427999 A1 19941208; AU 7070494 A 19941220; EP 0701560 A1 19960320; JP H09504775 A 19970513
DOCDB simple family (application)
EP 9401805 W 19940603; AU 7070494 A 19940603; EP 94919601 A 19940603; JP 52583294 A 19940603