EP 0710102 A1 19960508 - STABILIZATION OF AEROSOLIZED PROTEINS
Title (en)
STABILIZATION OF AEROSOLIZED PROTEINS
Title (de)
STABILISIERUNG VON PROTEINEN IN AEROSOLFORM
Title (fr)
STABILISATION DE PROTEINES ADMINISTREES DANS UN AEROSOL
Publication
Application
Priority
- US 9408136 W 19940719
- US 9384093 A 19930719
Abstract (en)
[origin: WO9503034A1] The present invention provides a method for protecting proteins against aerosolization-induced degradation and loss of protein activity. The aerosolized proteins are stabilized by adding a water soluble polar organic compound, such as polyethylene glycol, or a surfactant to the aqueous solution prior to aerosolization. The present invention further provides a stabilized aqueous protein solution containing a polar organic compound or surfactant and a system for aerosolizing the stabilized aqueous protein-containing solution.
IPC 1-7
IPC 8 full level
A61K 9/00 (2006.01); A61K 9/12 (2006.01); A61K 38/00 (2006.01); A61K 47/10 (2006.01); A61M 15/00 (2006.01); C07K 14/535 (2006.01); C12N 9/96 (2006.01)
CPC (source: EP)
A61K 9/0078 (2013.01); A61M 15/00 (2013.01); C07K 14/535 (2013.01); C12N 9/96 (2013.01)
Citation (search report)
See references of WO 9503034A1
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9503034 A1 19950202; AU 691514 B2 19980521; AU 7473294 A 19950220; CA 2167538 A1 19950202; EP 0710102 A1 19960508; FI 960253 A0 19960118; FI 960253 A 19960318; JP H09501418 A 19970210; NO 960217 D0 19960118; NO 960217 L 19960318; NZ 271181 A 19980626
DOCDB simple family (application)
US 9408136 W 19940719; AU 7473294 A 19940719; CA 2167538 A 19940719; EP 94924473 A 19940719; FI 960253 A 19960118; JP 50527194 A 19940719; NO 960217 A 19960118; NZ 27118194 A 19940719