EP 0716694 A4 19970604 - HUMAN GLUCAGON-LIKE 1 PEPTIDE RECEPTOR
Title (en)
HUMAN GLUCAGON-LIKE 1 PEPTIDE RECEPTOR
Title (de)
REZEPTOR FÜR MENSCHLICHES GLUCAGON-ÄHNLICHES 1 PEPTID
Title (fr)
UTILISATION DE L'HORMONE HUMAINE GLUCAGON COMME RECEPTEUR DE PEPTIDES 1
Publication
Application
Priority
- US 9408913 W 19940803
- US 10451793 A 19930809
Abstract (en)
[origin: WO9504821A1] The human GLP-1 receptor is cloned and used in an in vitro assay to screen for compounds that specifically bind to the human GLP-1 receptor, including compounds effective to reduce symptoms of diabetes. The invention includes the assay, the cloned human receptor used in the assay, an isolated human GLP-1 receptor free of other human proteins, and compounds identified through the use of this novel, cloned receptor, which selectively bind the human GLP-1 receptor.
IPC 1-7
IPC 8 full level
C12N 15/09 (2006.01); A61K 38/26 (2006.01); A61P 3/08 (2006.01); A61P 3/10 (2006.01); C07H 21/04 (2006.01); C07K 14/605 (2006.01); C07K 14/72 (2006.01); C12N 5/10 (2006.01); C12N 15/12 (2006.01); C12P 21/02 (2006.01); C12Q 1/02 (2006.01); C12R 1/91 (2006.01)
CPC (source: EP)
A61P 3/08 (2017.12); A61P 3/10 (2017.12); C07K 14/605 (2013.01); C07K 14/72 (2013.01)
Citation (search report)
- [PX] WO 9319175 A1 19930930 - THORENS BERNARD [CH]
- [PX] GRAZIANO MP ET AL: "Cloning and functional expression of a human glucagon-like peptide-1 receptor.", BIOCHEM BIOPHYS RES COMMUN, OCT 15 1993, 196 (1) P141-6, UNITED STATES, XP002028256
- See references of WO 9504821A1
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IE IT LI LU NL PT SE
DOCDB simple family (publication)
WO 9504821 A1 19950216; CA 2168448 A1 19950216; EP 0716694 A1 19960619; EP 0716694 A4 19970604; JP H09501054 A 19970204
DOCDB simple family (application)
US 9408913 W 19940803; CA 2168448 A 19940803; EP 94925207 A 19940803; JP 50655495 A 19940803