EP 0719262 A1 19960703 - 3,4-DIHYDRO-2H-1,2,4-BENZOTHIADIAZINE 1,1-DIOXIDE-3-CARBOXYLIC ACID DERIVATIVES, THEIR PREPARATION AND DRUGS CONTAINING SAME
Title (en)
3,4-DIHYDRO-2H-1,2,4-BENZOTHIADIAZINE 1,1-DIOXIDE-3-CARBOXYLIC ACID DERIVATIVES, THEIR PREPARATION AND DRUGS CONTAINING SAME
Title (de)
DERIVATE VON 3,4-DIHYDRO-2H-1,2,4-BENZOTHIADIAZINE 1,1-DIOXYD-3-CARBONSÄURE, IHRE HERSTELLUNG UND DIESE ENTHALTENDE MEDIKAMENTE
Title (fr)
DERIVES D'ACIDE 3,4-DIHYDRO-2H-1,2,4-BENZOTHIADIAZINE 1,1-DIOXYDE-3-CARBOXYLIQUE, LEUR PREPARATION ET LES MEDICAMENTS LES CONTENANT
Publication
Application
Priority
- FR 9401069 W 19940912
- FR 9311089 A 19930917
Abstract (en)
[origin: WO9507899A1] Compounds of formula (I) wherein R1 is a carboxy, alkoxycarbonyl, tetrazolyl, -CO-NH2, -CO-NH-alk, -CO-N(alk)2, -CO-NHOH, -CO-N(alk)OH, -CO-NH-O-R10, -CO-N(alk)-OR10 radical or a group convertible in vivo into a carboxy radical, R2, R3 and R4, which are the same or different, are hydrogen or halogen atoms or alkyl or alkoxy radicals, R5 is a hydroxy, -NHOH, -NH-CO-NH2, -CH2-NH2, hydroxyalkyl, alkoxyalkyl or -alk=NOH radical, R6, R7, R8 and R9, which are the same or different, are hydrogen or halogen atoms or alkyl, alkoxy, polyfluoroalkyl, amino, nitro, cyano, phenyl, vinyl, polyfluoroalkoxy, alkoxycarbonyl, carboxy, phenylalkyloxy, phenylalkyl, benzoylamino, phenylcarbonyl, hydroxy, -NHOH, -NH-CO-NH2, -CH2-NH2, hydroxyalkyl, alkoxyalkyl, -alk=NOH or phenoxy, with the phenyl ring being optionally substituted by one or several substituents selected from the halogen atoms and the alkyl, alkoxy or polyfluoroalkyl radicals, R10 is an alkyl or phenylalkyl radical and alk is an alkyl or alkylene radical. The invention also concerns the salts of thereof, the preparation thereof, and drugs containing same.
IPC 1-7
IPC 8 full level
A61K 31/54 (2006.01); A61K 31/5415 (2006.01); A61P 9/00 (2006.01); A61P 9/02 (2006.01); A61P 9/08 (2006.01); A61P 9/10 (2006.01); A61P 25/00 (2006.01); A61P 25/18 (2006.01); A61P 25/28 (2006.01); A61P 43/00 (2006.01); C07D 285/24 (2006.01); H04N 5/64 (2006.01)
CPC (source: EP)
A61P 9/00 (2017.12); A61P 9/02 (2017.12); A61P 9/08 (2017.12); A61P 9/10 (2017.12); A61P 25/00 (2017.12); A61P 25/18 (2017.12); A61P 25/28 (2017.12); A61P 43/00 (2017.12); C07D 285/24 (2013.01)
Citation (search report)
See references of WO 9507899A1
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IE IT LI LU NL PT SE
DOCDB simple family (publication)
WO 9507899 A1 19950323; AU 7660194 A 19950403; EP 0719262 A1 19960703; FR 2710062 A1 19950324; FR 2710062 B1 19951201; IL 110940 A0 19941128; JP H09502711 A 19970318; ZA 946930 B 19950412
DOCDB simple family (application)
FR 9401069 W 19940912; AU 7660194 A 19940912; EP 94926976 A 19940912; FR 9311089 A 19930917; IL 11094094 A 19940912; JP 50902095 A 19940912; ZA 946930 A 19940908