Global Patent Index - EP 0722330 A4

EP 0722330 A4 19970910 - METHODS FOR ANALYSIS OF HUMAN STEM CELLS

Title (en)

METHODS FOR ANALYSIS OF HUMAN STEM CELLS

Title (de)

METHODEN ZUR ANALYSE VON HUMANEN STAMMZELLEN

Title (fr)

METHODE D'ANALYSE DES CELLULES-SOUCHES HUMAINES

Publication

EP 0722330 A4 19970910 (EN)

Application

EP 94931328 A 19941007

Priority

  • US 9411456 W 19941007
  • US 13280993 A 19931007

Abstract (en)

[origin: WO9509640A1] The present invention provides methods for precisely and reproducibly assaying hematopoietic stem cell activity in a cell population and methods of using the assay. By expansion of hematopoietic stem cells identified by means of this assay, one may produce highly enriched or clonal populations of hematopoietic stem cells. The present invention also provides methods for producing enriched or clonal populations of other hematopoietic cell types, hematopoietic cells produced thereby, and methods of using the hematopoietic cells.

IPC 1-7

A61K 35/14; C12N 5/06; C12N 5/08; G01N 33/533; G01N 33/536

IPC 8 full level

C12N 5/0789 (2010.01); G01N 33/50 (2006.01); A61K 35/12 (2015.01); A61K 48/00 (2006.01)

CPC (source: EP)

C12N 5/0647 (2013.01); G01N 33/5094 (2013.01); A61K 48/00 (2013.01); A61K 2035/124 (2013.01); C12N 2501/125 (2013.01); C12N 2501/2303 (2013.01); C12N 2501/2306 (2013.01); C12N 2501/235 (2013.01); C12N 2502/1394 (2013.01)

Citation (search report)

  • [X] SROUR E.F. ET AL.: "Long-Term Generation and Expansion of Human Primitive Hematopoietic Progenitor Cells in Vitro", BLOOD, vol. 81, no. 3, 1 February 1993 (1993-02-01), pages 661 - 669, XP002035018
  • [A] WOLF N S ET AL: "IN VIVO AND IN VITRO CHARACTERIZATION OF LONG-TERM REPOPULATING PRIMITIVE HEMATOPOIETIC CELLS ISOLATED BY SEQUENTIAL HOECHST 33342-RHODAMINE 123 FACS SELECTION", EXPERIMENTAL HEMATOLOGY, vol. 21, no. 5, May 1993 (1993-05-01), pages 614 - 622, XP000604780
  • [PX] XIAO M. ET AL.: "Extensive Proliferation Capacity of Single Isolated CD34+++ Human Cord Blood Cells in Suspension Culture", BLOOD CELLS, vol. 20, no. 2-3, 1994, pages 455 - 466, XP002035019
  • See references of WO 9509640A1

Designated contracting state (EPC)

AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE

DOCDB simple family (publication)

WO 9509640 A1 19950413; AU 8014694 A 19950501; CA 2173726 A1 19950413; EP 0722330 A1 19960724; EP 0722330 A4 19970910

DOCDB simple family (application)

US 9411456 W 19941007; AU 8014694 A 19941007; CA 2173726 A 19941007; EP 94931328 A 19941007