EP 0722449 A1 19960724 - BOROPEPTIDE INHIBITORS OF THROMBIN WHICH CONTAIN A SUBSTITUTED PYRROLIDINE RING
Title (en)
BOROPEPTIDE INHIBITORS OF THROMBIN WHICH CONTAIN A SUBSTITUTED PYRROLIDINE RING
Title (de)
BOROPEPTID THROMBIN-INHIBITOREN, WELCHE EINEN SUBSTITUIERTEN PYRROLIDINRING ENTHALTEN
Title (fr)
INHIBITEURS BOROPEPTIDIQUES DE LA THROMBINE CONTENANT UN NOYAU DE PYRROLIDINE SUBSTITUE
Publication
Application
Priority
- US 9411049 W 19941006
- US 13325093 A 19931007
- US 13944393 A 19931020
Abstract (en)
[origin: WO9509859A1] This invention relates to the discovery of novel and useful alpha -amino acid analogs, and the pharmaceutically acceptable salts and prodrugs thereof, containing a disubstituted pyrrolidine ring conjugated to an alpha -amino acid, useful as inhibitors of thrombin.
IPC 1-7
C07F 5/02; A61K 31/69; C07K 5/062; C07D 207/16; C07F 9/572; A61K 38/05
IPC 8 full level
C07D 207/26 (2006.01); C07F 5/02 (2006.01); C07F 9/572 (2006.01); C07K 5/06 (2006.01); A61K 38/00 (2006.01)
CPC (source: EP)
C07D 207/26 (2013.01); C07F 5/025 (2013.01); C07F 9/572 (2013.01); C07K 5/06165 (2013.01); C07K 5/06191 (2013.01); A61K 38/00 (2013.01)
Citation (search report)
See references of WO 9509859A1
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9509859 A1 19950413; AU 7922794 A 19950501; CA 2174311 A1 19950413; EP 0722449 A1 19960724
DOCDB simple family (application)
US 9411049 W 19941006; AU 7922794 A 19941006; CA 2174311 A 19941006; EP 94929943 A 19941006