EP 0724633 A1 19960807 - RECOMBINANT TRANSFERRINS, TRANSFERRIN HALF-MOLECULES AND MUTANTS THEREOF
Title (en)
RECOMBINANT TRANSFERRINS, TRANSFERRIN HALF-MOLECULES AND MUTANTS THEREOF
Title (de)
REKOMBINANTE TRANSFERRINE, TRANSFERRINHALBE MOLEKÜLEN UND MUTANTEN DAVON
Title (fr)
TRANSFERRINES RECOMBINEES, DEMI-MOLECULES DE TRANSFERRINE ET LEURS MUTANTS
Publication
Application
Priority
- US 9200928 W 19920206
- US 65286991 A 19910208
Abstract (en)
[origin: WO9213550A1] Recombinant transferrin, transferrin half-molecules and mutant transferrins having altered metal-binding or other properties are described. The recombinant transferrin molecules are expressed in functionnal form by stable eukaryotic cell lines such as baby hamster kidney cells transformed with an expression vector encoding the recombinant molecule. The recombinant transferrins can be used in metal chelation therapy to bind and clear excess toxic metals in patients suffering from metal overloads.
IPC 1-7
IPC 8 full level
C12N 15/09 (2006.01); A61K 38/16 (2006.01); C07K 14/79 (2006.01); C12N 5/10 (2006.01); C12N 15/00 (2006.01); C12P 21/02 (2006.01); A61K 38/00 (2006.01); C12R 1/91 (2006.01)
CPC (source: EP)
C07K 14/79 (2013.01); A61K 38/00 (2013.01)
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IT LI LU MC NL SE
DOCDB simple family (publication)
WO 9213550 A1 19920820; CA 2103583 A1 19920809; CA 2103583 C 20091013; EP 0724633 A1 19960807; EP 0724633 A4 19940701; JP H07502723 A 19950323
DOCDB simple family (application)
US 9200928 W 19920206; CA 2103583 A 19920206; EP 92906503 A 19920206; JP 50586592 A 19920206