EP 0726900 A1 19960821 - 7H-IMIDAZO(1,2-a)PYRAZINE-8-ONE NMDA RECEPTOR ANTAGONISTS
Title (en)
7H-IMIDAZO(1,2-a)PYRAZINE-8-ONE NMDA RECEPTOR ANTAGONISTS
Title (de)
7H-IMIDIZO-¬1,2-a PYRAZINE-8-ONDERIVATE ALS NMDA REZEPTOR ANTAGONISTEN
Title (fr)
7H-IMIDAZO(1,2-a)PYRAZINE-8-ONE ANTAGONISTES DU RECEPTEUR NMDA
Publication
Application
Priority
- FR 9401268 W 19941102
- FR 9313164 A 19931105
Abstract (en)
[origin: WO9512594A1] Drugs containing as the active ingredient at least one compound of formula (I), wherein R1 represents a hydrogen atom or an alkyl or phenyl radical, R2 represents (a) a phenyl radical, (b) a phenyl radical substituted by one or more substituents selected from halogen atoms and alkyl, alkoxy, polyfluoroalkyl, polyfluoroalkoxy, phenyl, nitro or cyano radicals, (c) a naphthyl radical, (d) a naphthyl radical substituted by one or more substituents selected from halogen atoms and alkyl, alkoxy, polyfluoroalkyl, polyfluoroalkoxy, phenyl, nitro or cyano radicals, (e) a 2-,3- or 4-pyridyl radical, (f) a 2-, 3- or 4-pyridiyl radical substituted by one or more substituents selected from halogen atoms and alkyl, alkoxy, polyfluoroalkyl, polyfluoroalkoxy, phenyl, nitro or cyano radicals, (g) a 2- or 3-furyl radical, (h) a 2- or 3-furyl radical substituted by one or several substituents selected from halogen atoms and alkyl, alkoxy, polyfluoroalkyl, polyfluoroalkoxy, phenyl, nitro or cyano radicals or a salt of such a compound. The invention concerns the novel compounds of formula (I) and their preparation.
IPC 1-7
IPC 8 full level
A61K 31/495 (2006.01); A61P 9/00 (2006.01); A61P 9/02 (2006.01); A61P 9/08 (2006.01); A61P 9/10 (2006.01); C07D 487/04 (2006.01)
CPC (source: EP)
A61P 9/00 (2017.12); A61P 9/02 (2017.12); A61P 9/08 (2017.12); A61P 9/10 (2017.12); C07D 487/04 (2013.01)
Citation (search report)
See references of WO 9512594A1
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IE IT LI LU NL PT SE
DOCDB simple family (publication)
WO 9512594 A1 19950511; AU 8109794 A 19950523; EP 0726900 A1 19960821; FR 2711993 A1 19950512; FR 2711993 B1 19951201; IL 111526 A0 19950124; JP H09504539 A 19970506; ZA 948592 B 19950623
DOCDB simple family (application)
FR 9401268 W 19941102; AU 8109794 A 19941102; EP 95900182 A 19941102; FR 9313164 A 19931105; IL 11152694 A 19941103; JP 51304894 A 19941102; ZA 948592 A 19941101