EP 0728131 A1 19960828 - NOVEL TAXOIDS, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
Title (en)
NOVEL TAXOIDS, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
Title (de)
TAXANE, IHRE HERSTELLUNG UND ZUSAMMMENSETZUNGEN DIE SIE ENTHALTEN
Title (fr)
NOUVEAUX TAXOIDES, LEUR PREPARATION ET LES COMPOSITIONS PHARMACEUTIQUES QUI LES CONTIENNENT
Publication
Application
Priority
- FR 9401283 W 19941107
- FR 9313233 A 19931108
Abstract (en)
[origin: WO9513271A1] Novel taxoids of general formula (I), their preparation and pharmaceutical compositions containing them. In general formula (I), Ar is an aryl, alkyl, alkenyl, cycloalkyl or cycloalkenyl radical; R is a hydrogen atom or an alkanoyl, alkyloxyacetyl or alkyl radical; R1 is a benzoyl radical or a radical of formula R2-O-CO-, wherein R2 is an optionally substituted alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkenyl, bicycloalkyl, phenyl, heterocyclyl radical and R3 is an alkyl, alkenyl, cycloalkyl, cycloalkenyl, bicycloalkyl, optionally substituted aryl (excepting non-substituted phenyl) or heterocyclyl radical. The novel products of general formula (I) have remarkable antitumor activity.
IPC 1-7
C07D 305/14; A61K 31/335; C07D 407/12; C07D 409/12; A61K 31/38
IPC 8 full level
A61K 31/335 (2006.01); A61K 31/337 (2006.01); A61P 35/00 (2006.01); C07D 305/14 (2006.01); C07D 407/12 (2006.01); C07D 409/12 (2006.01)
CPC (source: EP)
A61P 35/00 (2017.12); C07D 305/14 (2013.01); C07D 407/12 (2013.01); C07D 409/12 (2013.01)
Citation (search report)
See references of WO 9513271A1
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IE IT LI LU NL PT SE
DOCDB simple family (publication)
WO 9513271 A1 19950518; AU 686690 B2 19980212; AU 8147094 A 19950529; CA 2175384 A1 19950518; CN 1134700 A 19961030; CZ 133696 A3 19960814; EP 0728131 A1 19960828; FI 961938 A0 19960507; FI 961938 A 19960507; FR 2712288 A1 19950519; FR 2712288 B1 19960105; HU 9601219 D0 19960729; HU T75063 A 19970328; JP H09504801 A 19970513; PL 314234 A1 19960902; SK 57496 A3 19961002; ZA 948789 B 19950712
DOCDB simple family (application)
FR 9401283 W 19941107; AU 8147094 A 19941107; CA 2175384 A 19941107; CN 94194073 A 19941107; CZ 133696 A 19941107; EP 95900794 A 19941107; FI 961938 A 19960507; FR 9313233 A 19931108; HU 9601219 A 19941107; JP 51362695 A 19941107; PL 31423494 A 19941107; SK 57496 A 19941107; ZA 948789 A 19941107