EP 0729464 A1 19960904 - 5,6-DIHYDROPYRONE DERIVATIVES AS PROTEASE INHIBITORS AND ANTIVIRAL AGENTS
Title (en)
5,6-DIHYDROPYRONE DERIVATIVES AS PROTEASE INHIBITORS AND ANTIVIRAL AGENTS
Title (de)
5,6-DIHYDROPYRON DERIVATE ALS PROTEASE INHIBITOREN UND ANTIVIRUSMITTELN
Title (fr)
DERIVES DE LA 5,6-DIHYDROPYRONE EN TANT QU'INHIBITEURS DE LA PROTEASE ET AGENTS ANTIVIRAUX
Publication
Application
Priority
- US 9412269 W 19941026
- US 15544393 A 19931119
- US 31982094 A 19941012
Abstract (en)
[origin: WO9514012A1] The present invention relates to novel 5,6-dihydropyrone derivatives and related structures which potently inhibit the HIV aspartyl protease blocking HIV infectivity. The 5,6-dihydropyrone derivatives are useful in the development of therapies for the treatment of bacterial and viral infections and diseases, including AIDS. The present invention is also directed to methods of synthesis of multifunctionalized 5,6-dihydropyrones and of related structures.
IPC 1-7
C07D 309/32; C07D 211/86; C07C 323/22; C07D 335/02; C07D 405/12; C07D 407/06; C07D 309/38; A61K 31/365
IPC 8 full level
C07D 335/02 (2006.01); A61K 31/35 (2006.01); A61K 31/351 (2006.01); A61K 31/352 (2006.01); A61K 31/365 (2006.01); A61K 31/366 (2006.01); A61K 31/44 (2006.01); A61K 31/443 (2006.01); A61K 31/4433 (2006.01); A61K 31/48 (2006.01); A61P 31/04 (2006.01); A61P 31/12 (2006.01); A61P 31/18 (2006.01); C07C 323/22 (2006.01); C07C 381/04 (2006.01); C07D 211/84 (2006.01); C07D 211/86 (2006.01); C07D 309/32 (2006.01); C07D 309/38 (2006.01); C07D 311/96 (2006.01); C07D 405/04 (2006.01); C07D 405/12 (2006.01); C07D 407/06 (2006.01); C07D 409/04 (2006.01)
CPC (source: EP)
A61P 31/04 (2017.12); A61P 31/12 (2017.12); A61P 31/18 (2017.12); C07C 323/22 (2013.01); C07D 211/86 (2013.01); C07D 309/32 (2013.01); C07D 311/96 (2013.01); C07D 405/04 (2013.01); C07D 405/12 (2013.01); C07D 407/06 (2013.01); C07C 2601/16 (2017.04)
Citation (search report)
See references of WO 9514012A1
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9514012 A1 19950526; AT E263761 T1 20040415; AU 689158 B2 19980326; AU 8125694 A 19950606; CA 2176043 A1 19950526; DE 69433705 D1 20040513; DE 69433705 T2 20050310; DK 1142887 T3 20040621; EP 0729464 A1 19960904; ES 2219457 T3 20041201; FI 962022 A0 19960513; FI 962022 A 19960712; HR P940935 A2 19970430; HR P940935 B1 20040831; HU 9601348 D0 19960729; HU T77668 A 19980728; IL 111674 A0 19950124; JP 3684426 B2 20050817; JP H09505294 A 19970527; NO 316172 B1 20031222; NO 962017 D0 19960515; NO 962017 L 19960708; NZ 275961 A 20011130; PT 1142887 E 20040831; RU 2140917 C1 19991110; SI 1142887 T1 20040831
DOCDB simple family (application)
US 9412269 W 19941026; AT 01114943 T 19941026; AU 8125694 A 19941026; CA 2176043 A 19941026; DE 69433705 T 19941026; DK 01114943 T 19941026; EP 95900429 A 19941026; ES 01114943 T 19941026; FI 962022 A 19960513; HR P940935 A 19941117; HU 9601348 A 19941026; IL 11167494 A 19941117; JP 51445895 A 19941026; NO 962017 A 19960515; NZ 27596194 A 19941026; PT 01114943 T 19941026; RU 96113098 A 19941026; SI 9430463 T 19941026