EP 0730466 A1 19960911 - COMPOSITIONS AND METHODS FOR INHIBITING HEPATOCYTE INVASION BY MALARIAL SPOROZOITES
Title (en)
COMPOSITIONS AND METHODS FOR INHIBITING HEPATOCYTE INVASION BY MALARIAL SPOROZOITES
Title (de)
ZUSAMMENSETZUNGEN UND VERFAHREN ZUR HEMMUNG DER INVASION VON HEPATOZYTEN DURCH MALARIASPOROZOITEN
Title (fr)
COMPOSITIONS ET PROCEDES DESTINES A INHIBER L'INVASION DES HEPATOCYTES PAR LES SPOROZO TES DU PALUDISME
Publication
Application
Priority
- US 9410186 W 19940909
- US 11969493 A 19930910
Abstract (en)
[origin: WO9507094A1] There is provided peptide and mimetic inhibitors for the binding of a circumsporozoite polypeptide to receptors of hepatocytes from malaria-susceptible mammals. Aslo contemplated is a method of inhibiting the binding of a malaria sporozoites to hepatocytes susceptible to sporozoite invasion. A peptide of Region II+ of the circumsporozoite protein is also provided, as is a method of targeting the delivery of substances to hepatocytes.
IPC 1-7
IPC 8 full level
C07K 14/445 (2006.01); C07K 14/705 (2006.01); C12N 15/87 (2006.01); A61K 38/00 (2006.01)
CPC (source: EP)
C07K 14/445 (2013.01); C07K 14/705 (2013.01); C12N 15/87 (2013.01); A61K 38/00 (2013.01); Y02A 50/30 (2017.12)
Designated contracting state (EPC)
BE CH DE DK ES FR GB IT LI NL SE
DOCDB simple family (publication)
WO 9507094 A1 19950316; AU 7724894 A 19950327; CA 2171562 A1 19950316; EP 0730466 A1 19960911; EP 0730466 A4 19990414
DOCDB simple family (application)
US 9410186 W 19940909; AU 7724894 A 19940909; CA 2171562 A 19940909; EP 94928067 A 19940909