EP 0733070 A1 19960925 - PROCESS FOR GENERATING SPECIFIC ANTIBODIES
Title (en)
PROCESS FOR GENERATING SPECIFIC ANTIBODIES
Title (de)
Herstellungsverfahen für spezifische Antikörper
Title (fr)
PROCEDE DE GENERATION D'ANTICORPS SPECIFIQUES
Publication
Application
Priority
- US 9414106 W 19941208
- US 16402293 A 19931208
- US 35040094 A 19941206
Abstract (en)
[origin: WO9515982A2] The present invention relates to a method for generating an antibody which is specific for an immunorecessive epitope, and nucleic acid encoding the antibody. The subject method generally comprises the steps of generating a variegated display library of antibody variable regions, and selecting from the library those antibody variable regions which have a desired binding specificity for the immunorecessive epitope. The antibody variable regions used to generate the display library are cloned from an immunotolerance-derived antibody repertoire.
IPC 1-7
IPC 8 full level
G01N 33/531 (2006.01); C07K 16/00 (2006.01); C12N 1/21 (2006.01); C12N 15/09 (2006.01); C12N 15/62 (2006.01); C12P 21/08 (2006.01); C12R 1/19 (2006.01)
CPC (source: EP)
C07K 16/00 (2013.01); C12N 15/62 (2013.01); C07K 2319/00 (2013.01); C07K 2319/735 (2013.01)
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9515982 A2 19950615; WO 9515982 A3 19951228; AU 1432195 A 19950627; AU 696293 B2 19980903; EP 0733070 A1 19960925; JP H09506262 A 19970624
DOCDB simple family (application)
US 9414106 W 19941208; AU 1432195 A 19941208; EP 95905871 A 19941208; JP 51633795 A 19941208