EP 0734388 A1 19961002 - IMPROVED PROCESS FOR THE SYNTHESIS OF 2-AMINO-3,5-DIHYDRO-7-SUBSTITUTED-4H-PYRROLO¬3,2-d PYRIMIDIN-4-ONES
Title (en)
IMPROVED PROCESS FOR THE SYNTHESIS OF 2-AMINO-3,5-DIHYDRO-7-SUBSTITUTED-4H-PYRROLO¬3,2-d PYRIMIDIN-4-ONES
Title (de)
VERBESSERTES VERFAHREN FÜR DIE SYNTHESE VON 2-AMINO-3,5-DIHYDRO-7-SUBSTITUIERTE-4H-PYRROLO¬3,2-D PYRIMIDIN-4-ONE
Title (fr)
PROCEDE AMELIORE DE SYNTHESE DE 2-AMINO-3,5-DIHYDRO-4H-PYRROLO¬3,2-d PYRIMIDIN-4-ONES SUBSTITUEES EN POSITION 7
Publication
Application
Priority
- US 9412292 W 19941026
- US 16775193 A 19931215
Abstract (en)
[origin: US5386031A] An improved process for the preparation of 2-amino-3,5-dihydro-7-substituted-4H-pyrrolo[3,2-d]pyrimidin-4-ones is described wherein 2,6-diamino-3,5-dihydro-7-substituted-4H-pyrrolo[3,2-d]pyrimidin-4-one is converted to a diazonium salt which is subsequently catalytically hydrogenated to the desired compound, as well as valuable intermediates used in the process.
IPC 1-7
IPC 8 full level
A61K 31/505 (2006.01); A61P 19/06 (2006.01); A61P 37/00 (2006.01); C07D 487/04 (2006.01)
CPC (source: EP US)
A61P 19/06 (2017.12 - EP); A61P 37/00 (2017.12 - EP); C07D 487/04 (2013.01 - EP US)
Citation (search report)
See references of WO 9516689A1
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
US 5386031 A 19950131; AU 681203 B2 19970821; AU 8092294 A 19950703; CA 2176040 A1 19950622; EP 0734388 A1 19961002; HU 9601664 D0 19960828; HU T74688 A 19970128; JP H09506614 A 19970630; NO 305803 B1 19990726; NO 962542 D0 19960614; NO 962542 L 19960614; NZ 275334 A 19980126; WO 9516689 A1 19950622
DOCDB simple family (application)
US 16775193 A 19931215; AU 8092294 A 19941026; CA 2176040 A 19941026; EP 94932056 A 19941026; HU 9601664 A 19941026; JP 51674795 A 19941026; NO 962542 A 19960614; NZ 27533494 A 19941026; US 9412292 W 19941026