EP 0735887 A1 19961009 - -i(IN UTERO) GENE THERAPY FOR FETUSES
Title (en)
-i(IN UTERO) GENE THERAPY FOR FETUSES
Title (de)
GENTHERAPIE FÜR FÖTEN IM UTERUS
Title (fr)
THERAPIE GENIQUE -i(IN UTERO) DESTINEE AUX F TUS
Publication
Application
Priority
- US 9413811 W 19941202
- US 16175493 A 19931203
Abstract (en)
[origin: WO9515167A1] A process for effecting gene therapy in utero in a fetus, which comprises transducing fetal cells in vivo with at least one nucleic acid sequence encoding a therapeutic agent. The fetal cells may be transduced with a viral vector (such as a retroviral vector) which includes the nucleic acid sequence encoding the therapeutic agent. The viral vector may be contained in a viral supernatant which is administered to the fetus, or may be generated by a producer cell line which is administered to the fetus.
IPC 1-7
IPC 8 full level
C12N 15/09 (2006.01); A61K 31/715 (2006.01); A61K 35/76 (2006.01); A61K 38/00 (2006.01); A61K 38/16 (2006.01); A61K 38/43 (2006.01); A61K 48/00 (2006.01); A61P 43/00 (2006.01)
CPC (source: EP)
A61K 31/70 (2013.01); A61K 48/00 (2013.01); A61P 43/00 (2017.12)
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9515167 A1 19950608; CA 2177998 A1 19950608; EP 0735887 A1 19961009; EP 0735887 A4 19980715; JP H09507839 A 19970812
DOCDB simple family (application)
US 9413811 W 19941202; CA 2177998 A 19941202; EP 95903185 A 19941202; JP 51576295 A 19941202