EP 0736007 A4 19970319 - NON-PEPTIDE TACHYKININ RECEPTOR ANTAGONISTS
Title (en)
NON-PEPTIDE TACHYKININ RECEPTOR ANTAGONISTS
Title (de)
NICHT-PEPTIDISCHE TACHYKININ REZEPTOR ANTAGONISTEN
Title (fr)
ANTAGONISTES NON PEPTIDIQUES DES RECEPTEURS DES TACHYKININES
Publication
Application
Priority
- US 9414312 W 19941214
- US 17113493 A 19931221
Abstract (en)
[origin: WO9517382A1] This invention provides a series of substituted benzofurans and indoles useful as non-peptide tachykinin receptor antagonists. This invention also provides methods for treating or preventing conditions associated with an excess of tachykinins which methods comprise administration of one or more of the compounds of the instant invention as well as formulations employing the compounds of this invention.
IPC 1-7
C07D 209/04; C07D 307/78; C07D 401/10; C07D 403/10; C07D 405/10; C07D 413/10; A61K 31/35; A61K 31/40; A61K 31/44; A61K 31/55; A61K 31/405
IPC 8 full level
C07D 295/08 (2006.01); A61K 31/135 (2006.01); A61K 31/255 (2006.01); A61K 31/27 (2006.01); A61K 31/34 (2006.01); A61K 31/343 (2006.01); A61K 31/38 (2006.01); A61K 31/381 (2006.01); A61K 31/40 (2006.01); A61K 31/403 (2006.01); A61K 31/404 (2006.01); A61K 31/445 (2006.01); A61K 31/495 (2006.01); A61K 31/55 (2006.01); A61P 25/00 (2006.01); A61P 25/02 (2006.01); A61P 25/04 (2006.01); A61P 29/00 (2006.01); A61P 43/00 (2006.01); C07C 217/22 (2006.01); C07C 309/65 (2006.01); C07D 209/12 (2006.01); C07D 307/80 (2006.01); C07D 333/56 (2006.01)
CPC (source: EP)
A61P 25/00 (2017.12); A61P 25/02 (2017.12); A61P 25/04 (2017.12); A61P 29/00 (2017.12); A61P 43/00 (2017.12); C07D 209/12 (2013.01); C07D 307/80 (2013.01)
Citation (search report)
- [X] US 4024273 A 19770517 - BRENNER L MARTIN, et al
- [X] CHEMICAL ABSTRACTS, vol. 111, no. 7, 14 August 1989, Columbus, Ohio, US; abstract no. 57444n, DUNARI, NEELAM ET AL: "Structure-activity relationship of antiestrogens. ..." XP002023025 & J. MED. CHEM., vol. 32, no. 8, - 1989, pages 1700 - 1707
- [X] CHEMICAL ABSTRACTS, vol. 106, no. 9, 2 March 1987, Columbus, Ohio, US; abstract no. 60767x, DAI,DEZAI ET AL.: "Anticonvulsant and analgesic activities of ..." XP002023026 & NANJING YAOXUEYUAN XUEBAO, vol. 17, no. 3, - 1986, pages 225 - 228
- [X] CHEMICAL ABSTRACTS, vol. 105, no. 5, 4 August 1986, Columbus, Ohio, US; abstract no. 42591k, HUANG, WENLONG ET AL: "Synthesis of ..." XP002023027 & YAOXUE XUEBAO, vol. 20, no. 10, - 1985, pages 737 - 746
- [X] CHEMICAL ABSTRACTS, vol. 88, no. 3, 16 January 1978, Columbus, Ohio, US; abstract no. 22527w, INION, HENRI ET AL: "Study of the indole series. IV. ..." XP002023028 & EUR. J. MED. CHEM. - CHIM. THER., vol. 12, no. 5, - 1977, pages 483 - 487
- [X] CHEMICAL ABSTRACTS, vol. 99, no. 19, 7 November 1983, Columbus, Ohio, US; abstract no. 158165m, DURANI, N. ET AL: "A convenient synthesis of ..." XP002023029 & INDIAN J. CHEM., SECT. B, vol. 22b, no. 5, - 1983, pages 489 - 490
- See references of WO 9517382A1
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9517382 A1 19950629; AU 1339795 A 19950710; CA 2176130 A1 19950629; EP 0736007 A1 19961009; EP 0736007 A4 19970319; JP H09506898 A 19970708; MX PA99001870 A 20040906; ZA 9410040 B 19960618
DOCDB simple family (application)
US 9414312 W 19941214; AU 1339795 A 19941214; CA 2176130 A 19941214; EP 95904891 A 19941214; JP 51747895 A 19941214; MX 9901870 A 19990225; ZA 9410040 A 19941215