EP 0736101 A1 19961009 - ENZYMATIC METHOD FOR SYNTHESIS OF O-GLYCOSYLATED AMINO ACID OR PEPTIDE OR DERIVATIVES THEREOF
Title (en)
ENZYMATIC METHOD FOR SYNTHESIS OF O-GLYCOSYLATED AMINO ACID OR PEPTIDE OR DERIVATIVES THEREOF
Title (de)
Enzymatische Methode zur Synthese von O - glycosilierten Aminosäuren oder Peptiden oder entsprechenden Derivaten
Title (fr)
METHODE ENZYMATIQUE POUR LA SYNTHESE D'ACIDE AMINE OU DE PEPTIDE O-GLYCOSYLE OU DE DERIVES DE CES DERNIERS
Publication
Application
Priority
- IB 9400444 W 19941227
- SE 9304316 A 19931224
Abstract (en)
[origin: WO9518232A1] Present invention describes a method for synthesis of O-glycosylated amino acid or peptide or derivatives thereof, characterized by the use of a glycosyl donor which is a monosaccharide in pyranose or furanose form or which is an oligosaccharide, and by the use of an acceptor which is a hydroxyl group containing amino acid or peptide derivative which has been modified in its N-terminal alpha -amino group and in which the C-terminal carboxyl group is non-modified, employing an exo- or an endoglycosidase (EC 3.2) as catalyst in an equilibrium reaction and that the product is isolated from the reaction mixture or is used directly or after partial or complete isolation in a continued synthesis with chemical methods or with enzymatic methods.
IPC 1-7
IPC 8 full level
C12P 19/26 (2006.01); C12P 21/00 (2006.01)
CPC (source: EP)
C12P 19/26 (2013.01); C12P 21/005 (2013.01)
Citation (search report)
See references of WO 9518232A1
Designated contracting state (EPC)
DE FR GB SE
DOCDB simple family (publication)
WO 9518232 A1 19950706; AU 1249095 A 19950717; EP 0736101 A1 19961009; SE 9304316 D0 19931224
DOCDB simple family (application)
IB 9400444 W 19941227; AU 1249095 A 19941227; EP 95903439 A 19941227; SE 9304316 A 19931224