EP 0739218 A1 19961030 - CROSS-LINKED POLYETHYLENE OXIDE COATINGS TO IMPROVE THE BIOCOMPATIBILITY OF IMPLANTABLE MEDICAL DEVICES
Title (en)
CROSS-LINKED POLYETHYLENE OXIDE COATINGS TO IMPROVE THE BIOCOMPATIBILITY OF IMPLANTABLE MEDICAL DEVICES
Title (de)
AUFGETEILTES EINZELFUNKSTELLEN BÜNDELFUNK-KOMMUNIKATIONSYSTEM
Title (fr)
REVETEMENTS A BASE D'OXYDE DE POLYETHYLENE RETICULE DESTINES A AMELIORER LA COMPATIBILITE BIOLOGIQUE D'APPAREILS MEDICAUX DESTINES A ETRE IMPLANTES
Publication
Application
Priority
- US 9514912 W 19951116
- US 34067194 A 19941116
- US 34068194 A 19941116
Abstract (en)
[origin: WO9614887A1] Polyethylene oxide (PEO) coatings providing improved biocompatibility for implantable medical devices are disclosed. The PEO coatings comprise functionalized, end-capped PEO which is attached at one end to the medical device. The PEO compounds are then cross-linked by 1) exposure to a high energy source for a time sufficient to cause the PEO compounds to form a cross-linked, insoluble network or 2) by reacting the free functionalized ends of a sufficient number of bound PEO compounds with a crosslinking agent whose functional groups are reactive toward the bound PEO chain's functionalized ends. These PEO coatings are able to survive ethylene oxide sterilization procedures with minimal loss of protein or cell repulsion ability.
IPC 1-7
IPC 8 full level
A61L 27/00 (2006.01); A61L 2/20 (2006.01); A61L 27/34 (2006.01); A61L 29/08 (2006.01); A61L 33/00 (2006.01); A61L 33/06 (2006.01)
CPC (source: EP US)
A61F 2/16 (2013.01 - EP US); A61L 2/206 (2013.01 - EP US); A61L 27/34 (2013.01 - EP US); A61L 29/085 (2013.01 - EP); A61L 33/068 (2013.01 - EP)
Citation (search report)
See references of WO 9614887A1
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9614887 A1 19960523; AU 4162396 A 19960606; CA 2180147 A1 19960523; EP 0739218 A1 19961030; JP H09507784 A 19970812
DOCDB simple family (application)
US 9514912 W 19951116; AU 4162396 A 19951116; CA 2180147 A 19951116; EP 95939997 A 19951116; JP 51633396 A 19951116