Global Patent Index - EP 0739218 A1

EP 0739218 A1 19961030 - CROSS-LINKED POLYETHYLENE OXIDE COATINGS TO IMPROVE THE BIOCOMPATIBILITY OF IMPLANTABLE MEDICAL DEVICES

Title (en)

CROSS-LINKED POLYETHYLENE OXIDE COATINGS TO IMPROVE THE BIOCOMPATIBILITY OF IMPLANTABLE MEDICAL DEVICES

Title (de)

AUFGETEILTES EINZELFUNKSTELLEN BÜNDELFUNK-KOMMUNIKATIONSYSTEM

Title (fr)

REVETEMENTS A BASE D'OXYDE DE POLYETHYLENE RETICULE DESTINES A AMELIORER LA COMPATIBILITE BIOLOGIQUE D'APPAREILS MEDICAUX DESTINES A ETRE IMPLANTES

Publication

EP 0739218 A1 19961030 (EN)

Application

EP 95939997 A 19951116

Priority

  • US 9514912 W 19951116
  • US 34067194 A 19941116
  • US 34068194 A 19941116

Abstract (en)

[origin: WO9614887A1] Polyethylene oxide (PEO) coatings providing improved biocompatibility for implantable medical devices are disclosed. The PEO coatings comprise functionalized, end-capped PEO which is attached at one end to the medical device. The PEO compounds are then cross-linked by 1) exposure to a high energy source for a time sufficient to cause the PEO compounds to form a cross-linked, insoluble network or 2) by reacting the free functionalized ends of a sufficient number of bound PEO compounds with a crosslinking agent whose functional groups are reactive toward the bound PEO chain's functionalized ends. These PEO coatings are able to survive ethylene oxide sterilization procedures with minimal loss of protein or cell repulsion ability.

IPC 1-7

A61L 27/00

IPC 8 full level

A61L 27/00 (2006.01); A61L 2/20 (2006.01); A61L 27/34 (2006.01); A61L 29/08 (2006.01); A61L 33/00 (2006.01); A61L 33/06 (2006.01)

CPC (source: EP US)

A61F 2/16 (2013.01 - EP US); A61L 2/206 (2013.01 - EP US); A61L 27/34 (2013.01 - EP US); A61L 29/085 (2013.01 - EP); A61L 33/068 (2013.01 - EP)

C-Set (source: EP)

  1. A61L 27/34 + A61L 2/206 + A61F 2/16 + C08L 71/02
  2. A61L 27/34 + C08L 71/02
  3. A61L 29/085 + C08L 71/02
  4. A61L 33/068 + C08L 71/02

Citation (search report)

See references of WO 9614887A1

Designated contracting state (EPC)

AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE

DOCDB simple family (publication)

WO 9614887 A1 19960523; AU 4162396 A 19960606; CA 2180147 A1 19960523; EP 0739218 A1 19961030; JP H09507784 A 19970812

DOCDB simple family (application)

US 9514912 W 19951116; AU 4162396 A 19951116; CA 2180147 A 19951116; EP 95939997 A 19951116; JP 51633396 A 19951116