Global Patent Index - EP 0740791 A4

EP 0740791 A4 20000405 - SYSTEMATIC MODULAR PRODUCTION OF AMINIMIDE- AND OXAZOLONE-BASED MOLECULES HAVING SELECTED PROPERTIES

Title (en)

SYSTEMATIC MODULAR PRODUCTION OF AMINIMIDE- AND OXAZOLONE-BASED MOLECULES HAVING SELECTED PROPERTIES

Title (de)

SYSTEMATISCHE MODULARE HERSTELLUNG VON AMINIMID- UND OXAZOLONBASIERTEN MOLEKÜLEN MIT AUSGEWÄHLTEN EIGENSCHAFTEN

Title (fr)

PRODUCTION MODULAIRE SYSTEMATIQUE DE MOLECULES A BASE D'AMINIMIDE ET D'OXAZOLONE AYANT DES PROPRIETES CHOISIES

Publication

EP 0740791 A4 20000405 (EN)

Application

EP 94906537 A 19940105

Priority

  • US 9400199 W 19940105
  • CA 2180526 A 19940105

Abstract (en)

[origin: WO9518972A1] A method for obtaining compounds having selected properties for a particular application by forming base modules having at least two structural diversity elements from the reaction of a first compound having at least one structural diversity element and a first reactive group, with a second compound having at least one structural diversity element and a second reactive group, wherein the first and second groups combine by an addition reaction; producing a first array of molecules by varying at least one of the structural diversity elements of the compounds when producing the base modules; and screening the array to determine a first suitable compound for the particular application. The base modules are preferably formed from oxazolone- and aminimide-derived compounds. If desired, the method can be repeated by producing a second array of molecules through the formation of base modules having structural diversity elements that are modified from those of the first suitable compound; and screening the second array of molecules to determine a second suitable compound for the particular application. The second array producing and screening steps can be repeated as often as necessary to achieve an optimum compound for the particular application.

IPC 1-7

G01N 33/566

IPC 8 full level

G01N 33/48 (2006.01); C07B 61/00 (2006.01); C07C 243/40 (2006.01); C07D 263/42 (2006.01); C07D 265/10 (2006.01); C07D 267/06 (2006.01); C07D 295/32 (2006.01); C07D 307/54 (2006.01); C07D 333/24 (2006.01); C07D 405/12 (2006.01); C07D 409/12 (2006.01); C07D 413/12 (2006.01); C07K 5/00 (2006.01); C07K 7/00 (2006.01); C07K 14/00 (2006.01); G01N 33/53 (2006.01); G01N 33/566 (2006.01)

CPC (source: EP)

C07D 263/42 (2013.01); C07D 295/32 (2013.01); C07D 307/54 (2013.01); C07D 333/24 (2013.01); C40B 40/04 (2013.01); C40B 50/08 (2013.01)

Citation (search report)

  • [E] WO 9401102 A1 19940120 - LEGOMER PARTNERS LP [US], et al
  • [E] WO 9405394 A1 19940317 - ARRIS PHARM CORP [US]
  • [XY] WO 9309668 A1 19930527 - AFFYMAX TECH NV [NL]
  • [XY] FODOR S P A ET AL: "LIGHT-DIRECTED, SPATIALLY ADDRESSABLE PARALLEL CHEMICAL SYNTHESIS", SCIENCE,US,AMERICAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE,, vol. 251, no. 4995, 15 February 1991 (1991-02-15), pages 767 - 773, XP000486899, ISSN: 0036-8075
  • [XY] HOBBS DE WITT S ET AL: "DIVERSOMERS: AN APPROACH TO NONPEPTIDE, NONOLIGOMERIC CHEMICAL DIVERSITY", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA,US,NATIONAL ACADEMY OF SCIENCE. WASHINGTON, vol. 90, no. 15, 1 August 1993 (1993-08-01), pages 6909 - 6913, XP000651795, ISSN: 0027-8424
  • [XY] OHLMEYER M H J ET AL: "COMPLEX SYNTHETIC CHEMICAL LIBRARIES INDEXED WITH MOLECULAR TAGS", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA,US,NATIONAL ACADEMY OF SCIENCE. WASHINGTON, vol. 90, 1 December 1993 (1993-12-01), pages 10922 - 10926, XP000652270, ISSN: 0027-8424
  • [A] BHATIA S K ET AL: "NEW APPROACH TO PRODUCING PATTERNED BIOMOLECULAR ASSEMBLIES", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY,US,AMERICAN CHEMICAL SOCIETY, WASHINGTON, DC, vol. 114, 20 May 1992 (1992-05-20), pages 4432 - 4433, XP000867337, ISSN: 0002-7863
  • See references of WO 9518972A1

Designated contracting state (EPC)

AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE

DOCDB simple family (publication)

WO 9518972 A1 19950713; AU 6022194 A 19950801; AU 704183 B2 19990415; CA 2180526 A1 19950713; EP 0740791 A1 19961106; EP 0740791 A4 20000405; JP H09507487 A 19970729

DOCDB simple family (application)

US 9400199 W 19940105; AU 6022194 A 19940105; CA 2180526 A 19940105; EP 94906537 A 19940105; JP 51844695 A 19940105