Global Patent Index - EP 0745077 A1

EP 0745077 A1 19961204 - ENANTIOMERICALLY PURE (+)-LIAROZOLE

Title (en)

ENANTIOMERICALLY PURE (+)-LIAROZOLE

Title (de)

ENANTIOMERREINE (+)- LIAROZOLE

Title (fr)

(+)- LIAROZOLE PUR SUR LE PLAN ENANTIOMORPHE

Publication

EP 0745077 A1 19961204 (EN)

Application

EP 95907662 A 19950210

Priority

  • EP 95907662 A 19950210
  • EP 9500490 W 19950210
  • EP 94200420 A 19940218

Abstract (en)

[origin: WO9522540A1] This invention relates to the novel enantiomerically pure dextrorotatory isomer of liarozole of formula (I) and the pharmaceutically acceptable acid addition salt forms thereof. These compounds are particularly useful in treating disorders which are characterized by an increased proliferation and/or abnormal differentiation of normal, preneoplastic or neoplastic epithelial cells. These compounds are particularly useful in the field of dermatology. Also disclosed are compositions containing said novel compounds, methods of preparing said novel compounds as well as methods of using the mentioned compounds to treat the mentioned disorders.

IPC 1-7

C07D 403/06; C07D 233/16; A61K 31/415

IPC 8 full level

C07D 233/64 (2006.01); A61K 31/20 (2006.01); A61K 31/415 (2006.01); A61P 17/00 (2006.01); A61P 35/00 (2006.01); A61P 43/00 (2006.01); C07D 233/16 (2006.01); C07D 403/06 (2006.01); C07D 521/00 (2006.01)

CPC (source: EP)

A61P 17/00 (2017.12); A61P 35/00 (2017.12); A61P 43/00 (2017.12); C07D 231/12 (2013.01); C07D 233/56 (2013.01); C07D 249/08 (2013.01)

Citation (search report)

See references of WO 9522540A1

Designated contracting state (EPC)

AT BE CH DE DK ES FR GB GR IE IT LI LU NL PT SE

DOCDB simple family (publication)

WO 9522540 A1 19950824; AU 1578795 A 19950904; AU 689206 B2 19980326; CA 2182583 A1 19950824; CN 1141042 A 19970122; EP 0745077 A1 19961204; IL 112688 A0 19950526; JP H09508914 A 19970909; MX 9603316 A 19970228; NZ 279227 A 19971124; SG 52325 A1 19980928; TW 401415 B 20000811; ZA 951343 B 19960819

DOCDB simple family (application)

EP 9500490 W 19950210; AU 1578795 A 19950210; CA 2182583 A 19950210; CN 95191684 A 19950210; EP 95907662 A 19950210; IL 11268895 A 19950217; JP 52156395 A 19950210; MX 9603316 A 19950210; NZ 27922795 A 19950210; SG 1996002813 A 19950210; TW 84101153 A 19950210; ZA 951343 A 19950217