Global Patent Index - EP 0749314 A4

EP 0749314 A4 20020918 - METHOD FOR TREATING AND INHIBITING GASTRIC AND DUODENAL ULCERS

Title (en)

METHOD FOR TREATING AND INHIBITING GASTRIC AND DUODENAL ULCERS

Title (de)

VERFAHREN ZUR BEHANDLUNG UND INHIBIERUNG DER MAGEN- UND ZWÖLFFINGERDARMGESCHWÜREN

Title (fr)

PROCEDE DE TRAITEMENT ET D'INHIBITION DES ULCERES GASTRIQUES ET DUODENAUX

Publication

EP 0749314 A4 20020918 (EN)

Application

EP 95911945 A 19950302

Priority

  • US 9502388 W 19950302
  • US 20451594 A 19940302

Abstract (en)

[origin: WO9523605A1] A method for treating and/or inhibiting gastric and duodenal ulcers, comprising administering a pharmaceutical composition comprising an oligosaccharide of the following formula (I): (NeuAc- alpha (2-3)-pGal- beta (1)-(-X-)m-(-Y-)n-)p-Z wherein X is a chemical bond or a group capable of linking the p galactose to either the linking group Y or the multivalent support Z; wherein the C1 glycosidic oxygen of galactose may be replaced by N, S or C; Y is a linking group; Z is a multivalent support; m is 0 or 1; n is 0 or 1; and p is an integer of 2-1,000 is described. Also described is a method for treating and/or inhibiting gastric and duodenal ulcers, comprising administering a pharmaceutical composition comprising an oligosaccharide of the formula (II): NeuAc- alpha (2-3)-pGal- beta (1)-A wherein A is a group capable of bonding to the p galactose; wherein the C1 glycosidic oxygen of galactose may be replaced by N, S or C.

IPC 1-7

A61K 31/715; A61K 31/70; A61K 45/06

IPC 8 full level

A61K 31/70 (2006.01); A61K 31/7012 (2006.01); A61K 31/702 (2006.01); A61K 31/7024 (2006.01); A61K 45/06 (2006.01); A61K 47/48 (2006.01); A61P 1/04 (2006.01); A61P 31/04 (2006.01); C07H 7/027 (2006.01); C07H 13/06 (2006.01)

CPC (source: EP)

A61K 31/70 (2013.01); A61K 31/715 (2013.01); A61K 45/06 (2013.01); A61P 1/04 (2017.12); A61P 31/04 (2017.12)

Citation (search report)

  • [X] WO 9403184 A1 19940217 - NEOSE PHARM INC [US]
  • [A] WO 9318775 A1 19930930 - UNIV BRITISH COLUMBIA [CA]
  • [A] WO 9323055 A1 19931125 - UNIV BRITISH COLUMBIA [CA], et al
  • [A] FR 2662697 A1 19911206 - SNOW BRAND MILK PROD CO LTD [JP]
  • [A] FALK P ET AL: "AN IN VITRO ADHERENCE ASSAY REVEALS THAT HELICOBACTER PYLORI EXHIBITS CELL LINEAGE-SPECIFIC TROPISM IN THE HUMAN GASTRIC EPITHELIUM", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE. WASHINGTON, US, vol. 90, no. 5, 1 March 1993 (1993-03-01), pages 2035 - 2039, XP000560389, ISSN: 0027-8424
  • See references of WO 9523605A1

Designated contracting state (EPC)

AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE

DOCDB simple family (publication)

WO 9523605 A1 19950908; AU 1932395 A 19950918; AU 709149 B2 19990819; CA 2183329 A1 19950908; EP 0749314 A1 19961227; EP 0749314 A4 20020918; JP 3179108 B2 20010625; JP H09509931 A 19971007

DOCDB simple family (application)

US 9502388 W 19950302; AU 1932395 A 19950302; CA 2183329 A 19950302; EP 95911945 A 19950302; JP 52295595 A 19950302