EP 0753062 A1 19970115 - RIBOZYMES TARGETING THE RETROVIRAL PACKAGING SEQUENCE EXPRESSION CONSTRUCTS AND RECOMBINANT RETROVIRUSES CONTAINING SUCH CONSTRUCTS
Title (en)
RIBOZYMES TARGETING THE RETROVIRAL PACKAGING SEQUENCE EXPRESSION CONSTRUCTS AND RECOMBINANT RETROVIRUSES CONTAINING SUCH CONSTRUCTS
Title (de)
RIBOZYME WELCHE AUF DIE RETROVIRALEN VERPACKUNGSSEQUENZEN VON EXPRESSIONSPRODUKTEN ZIELEN UND REKOMBINANTE RETROVIREN SOLCHE KONSTRUKTE ENTHALTEND
Title (fr)
RIBOZYMES CIBLANT LES PRODUITS DE RECOMBINAISON D'EXPRESSION DE SEQUENCES D'ENCAPSIDATION RETROVIRALES ET RETROVIRUS RECOMBINES CONTENANT LESDITS PRODUITS DE RECOMBINAISON
Publication
Application
Priority
- IB 9500050 W 19950105
- US 17808294 A 19940105
- US 31025994 A 19940921
Abstract (en)
[origin: EP1298208A2] The present invention concerns an oligonucleotide compound, which comprises a ribozyme targeted to the GUA target site at nucleotide 5849 of the HIV-1 SF-2 isolate or a corresponding target site of other HIV-1 isolates. The invention also relates to transfer vectors comprised of RNA or DNA or a combination thereof which on transcription give rise to said compound, to cells comprising a nucleotide sequence which is, or on transcription gives rise to, said compound and to pharmaceutical compositions containing said compound or said transfer vector. <IMAGE>
IPC 1-7
C12N 15/11; C12N 15/48; C12N 15/49; C12N 15/74; C12N 15/79; C12N 15/85; C12N 5/10; C07H 21/02; A61K 31/70; A61K 48/00
IPC 8 full level
C12N 15/09 (2006.01); A01N 63/00 (2006.01); A61K 31/70 (2006.01); A61K 35/26 (2006.01); A61K 35/28 (2006.01); A61K 35/76 (2006.01); A61K 48/00 (2006.01); A61P 1/16 (2006.01); A61P 31/12 (2006.01); A61P 31/18 (2006.01); A61P 33/02 (2006.01); A61P 35/02 (2006.01); A61P 37/04 (2006.01); C07H 21/04 (2006.01); C12N 5/10 (2006.01); C12N 15/00 (2006.01); C12N 15/113 (2010.01); C12Q 1/68 (2006.01); A61K 38/00 (2006.01); C12R 1/92 (2006.01)
CPC (source: EP)
A61P 1/16 (2018.01); A61P 31/12 (2018.01); A61P 31/18 (2018.01); A61P 33/02 (2018.01); A61P 35/02 (2018.01); A61P 37/04 (2018.01); C12N 15/113 (2013.01); C12N 15/1131 (2013.01); C12N 15/1132 (2013.01); A61K 38/00 (2013.01); C12N 2310/111 (2013.01); C12N 2310/12 (2013.01); C12N 2310/121 (2013.01); C12N 2310/122 (2013.01)
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9518854 A1 19950713; AT E320487 T1 20060415; AU 1391295 A 19950801; AU 698730 B2 19981105; CA 2180358 A1 19950713; CN 1145638 A 19970319; CN 1267552 C 20060802; DE 69534864 D1 20060511; DE 69534864 T2 20070222; DK 1298208 T3 20060724; EP 0753062 A1 19970115; EP 0753062 A4 19991020; EP 1298208 A2 20030402; EP 1298208 A3 20040107; EP 1298208 B1 20060315; ES 2260376 T3 20061101; IL 112261 A0 19950330; IL 112261 A 20050831; JP 3691849 B2 20050907; JP H09508004 A 19970819; NO 319376 B1 20050725; NO 962826 D0 19960704; NO 962826 L 19960827; NZ 278432 A 19980626; PT 1298208 E 20061031
DOCDB simple family (application)
IB 9500050 W 19950105; AT 02025406 T 19950105; AU 1391295 A 19950105; CA 2180358 A 19950105; CN 95191931 A 19950105; DE 69534864 T 19950105; DK 02025406 T 19950105; EP 02025406 A 19950105; EP 95905220 A 19950105; ES 02025406 T 19950105; IL 11226195 A 19950105; JP 51840395 A 19950105; NO 962826 A 19960704; NZ 27843295 A 19950105; PT 02025406 T 19950105