EP 0753069 A1 19970115 - GENE DELIVERY FUSION PROTEINS
Title (en)
GENE DELIVERY FUSION PROTEINS
Title (de)
Fusionsprotein für Gentransfer
Title (fr)
PROTEINE DE FUSION D'APPORT DE GENE
Publication
Application
Priority
- US 9504738 W 19950417
- US 22785894 A 19940415
- US 32646094 A 19941019
Abstract (en)
[origin: WO9528494A1] The invention provides gene delivery fusion protein (GDFPs) for use in gene transduction of target cells, such as mammalian cells. The GDFP contains a nucleic acid binding domain (NBD) that binds to a targeted nucleic acid to be transduced, fused to a gene delivery domain (GDD) that mediates or augments transfer of the targeted nucleic acid into the target cell. The GDD contains one or more components that facilitate gene delivery, including binding/targetting components, membrane-disrupting components, transport/localization components and replicon integration components.
IPC 1-7
IPC 8 full level
C12N 15/09 (2006.01); A61K 38/00 (2006.01); A61K 47/48 (2006.01); A61K 48/00 (2006.01); C07K 14/395 (2006.01); C07K 14/55 (2006.01); C07K 19/00 (2006.01); C12N 5/10 (2006.01); C12N 15/87 (2006.01)
CPC (source: EP)
A61K 47/6425 (2017.07); C07K 14/395 (2013.01); C07K 14/55 (2013.01); C12N 15/87 (2013.01); A61K 48/00 (2013.01); C07K 2319/00 (2013.01)
Citation (search report)
See references of WO 9528494A1
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9528494 A1 19951026; AU 2387295 A 19951110; AU 706572 B2 19990617; CA 2187818 A1 19951026; EP 0753069 A1 19970115; JP H10501963 A 19980224
DOCDB simple family (application)
US 9504738 W 19950417; AU 2387295 A 19950417; CA 2187818 A 19950417; EP 95917029 A 19950417; JP 52715795 A 19950417