Global Patent Index - EP 0753580 A2

EP 0753580 A2 19970115 - Cell-specific gene therapy, using the tissue inhibitor of metalloproteinase-3 promoter

Title (en)

Cell-specific gene therapy, using the tissue inhibitor of metalloproteinase-3 promoter

Title (de)

Zellspezifische Gentherapie mit Hilfe eines neuen Promotors für den "Tissue Inhibitor of Metalloproteinase-3"

Title (fr)

Thérapie génique à spécificité cellulaire, utilisant le promoteur de l'inhibiteur de métalloprotéinases d'origine tissulaire du type 3

Publication

EP 0753580 A2 19970115 (DE)

Application

EP 96110962 A 19960708

Priority

DE 19524720 A 19950712

Abstract (en)

Agent for preventing or treating diseases involving the immune system contains a DNA construct (I) that comprises an activator sequence (AS); cell-cycle regulated promoter module (PM) and DNA sequence (II) encoding an active cpd. (A).

Abstract (de)

Die Erfindung betrifft Promotorsequenzen für das Gen des <IMAGE>Tissue Inhibitors of Metalloproteinase-3" (TIMP-3). Diese Inhibitor kommt besonders in Makrophagen und Synovialzellen der Gelenke vor.

IPC 1-7

C12N 15/85; A61K 48/00

IPC 8 full level

A61K 48/00 (2006.01); A61P 43/00 (2006.01); C07H 21/04 (2006.01); C12N 1/21 (2006.01); C12N 5/10 (2006.01); C12N 15/09 (2006.01); C12N 15/85 (2006.01)

CPC (source: EP US)

A61K 48/00 (2013.01 - EP US); A61P 43/00 (2017.12 - EP); C12N 15/85 (2013.01 - EP US); C12N 2830/008 (2013.01 - EP US)

Designated contracting state (EPC)

AT BE CH DE DK ES FR GB GR IE IT LI LU NL PT SE

DOCDB simple family (publication)

US 5854019 A 19981229; CA 2181022 A1 19970113; DE 19524720 A1 19970116; EP 0753580 A2 19970115; EP 0753580 A3 19981007; JP H0923889 A 19970128

DOCDB simple family (application)

US 67921796 A 19960712; CA 2181022 A 19960711; DE 19524720 A 19950712; EP 96110962 A 19960708; JP 18176096 A 19960711