EP 0756603 A1 19970205 - MULTIREPRESENTATION OF A PEPTIDE ANALOGUE OF THE DPPIV SUBSTRATE, ESPECIALLY OF THE KPR TYPE, TO INHIBIT THE ENTRY OF HIV IN CELLS

Title (en)

MULTIREPRESENTATION OF A PEPTIDE ANALOGUE OF THE DPPIV SUBSTRATE, ESPECIALLY OF THE KPR TYPE, TO INHIBIT THE ENTRY OF HIV IN CELLS

Title (de)

MULTIREPRÄSENTATION EINES PEPTIDANALOGS DES DPP4-SUBSTRATS, BESONDERS VOM TYP KPR, INHIBIERUNG DES HIV-ZUTRITTES IN DIE ZELLEN

Title (fr)

MULTIREPRESENTATION D'UN ANALOGUE PEPTIDIQUE DU SUBSTRAT DE LA DPPIV, NOTAMMENT DE TYPE KPR, AFIN D'INHIBER L'ENTREE DU HIV DANS LES CELLULES

Publication

EP 0756603 A1 19970205 (FR)

Application

EP 95918043 A 19950421

Priority

FR 9500528 W 19950421
FR 9404895 A 19940422

Abstract (en)

[origin: WO9529190A1] Molecule comprising a plurality of repeat patterns, especially of the KPR type, which are recognizable by an ectoprotein (on the cell surface) in particular by the CD26 receptor (also known as the DPPIV enzyme). Said patterns are all carried by a peptide matrix enabling their multiple presentation to the enzyme and having an affinity for the latter. Said molecule is the active ingredient of a composition inhibiting the entry of HIV in cells, in particular, for the treatment of a retrovirus-induced infection.

IPC 1-7

C07K 14/16; A61K 38/00

IPC 8 full level

A61K 38/00 (2006.01); A61P 31/12 (2006.01); A61P 37/04 (2006.01); C07K 5/068 (2006.01); C07K 5/078 (2006.01); C07K 5/09 (2006.01); C07K 5/097 (2006.01); C07K 5/103 (2006.01); C07K 5/11 (2006.01); C07K 7/06 (2006.01); C07K 14/155 (2006.01); C07K 14/16 (2006.01); C07K 17/02 (2006.01); A61K 39/00 (2006.01)

CPC (source: EP US)

A61P 31/12 (2018.01 - EP); A61P 37/04 (2018.01 - EP); C07K 14/005 (2013.01 - EP); A61K 38/00 (2013.01 - EP); A61K 39/00 (2013.01 - EP US); C12N 2740/16122 (2013.01 - EP)

Designated contracting state (EPC)

AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE

DOCDB simple family (publication)

WO 9529190 A1 19951102; AU 2412595 A 19951116; CA 2188470 A1 19951102; EP 0756603 A1 19970205; FR 2719049 A1 19951027; FR 2719049 B1 19960614; JP H10502337 A 19980303

DOCDB simple family (application)

FR 9500528 W 19950421; AU 2412595 A 19950421; CA 2188470 A 19950421; EP 95918043 A 19950421; FR 9404895 A 19940422; JP 52740695 A 19950421