Global Patent Index - EP 0757558 A4

EP 0757558 A4 19990616 - SCREENING METHODS FOR INTEGUMENTAL INFLAMMATION MODULATING AGENTS

Title (en)

SCREENING METHODS FOR INTEGUMENTAL INFLAMMATION MODULATING AGENTS

Title (de)

METHODE ZUM AUFFINDEN VON AGENTIEN, DIE EINE ENTZÜNDLICHE HAUTREAKTION MODULIEREN

Title (fr)

PROCEDES DE CRIBLAGE DES AGENTS MODULATEURS DES INFLAMMATIONS TEGUMENTAIRES

Publication

EP 0757558 A4 19990616 (EN)

Application

EP 95917009 A 19950411

Priority

  • US 9504677 W 19950411
  • US 22599194 A 19940412
  • US 27128794 A 19940706
  • US 40023495 A 19950303

Abstract (en)

[origin: WO9527510A1] The present invention provides a number of screening methods for evaluating compounds capable of suppressing cytokine production either in vitro or in vivo. The methods generally involve stimulating the production of a cytokine in a cell, exposing a portion of the cells to a putative cytokine modulating agent and determining subsequent levels of cytokine production in the cells. Additionally, the present invention provides certain compounds identified by this method.

IPC 1-7

A61K 45/00; C12N 15/00; C12N 15/09; C12N 15/19; C12Q 1/00; C12Q 1/66; G01N 33/53

IPC 8 full level

A61N 1/30 (2006.01); A61K 31/00 (2006.01); A61K 31/277 (2006.01); A61K 31/341 (2006.01); A61K 31/4174 (2006.01); A61K 31/4422 (2006.01); A61K 31/451 (2006.01); A61K 31/522 (2006.01); A61K 31/554 (2006.01); A61K 31/585 (2006.01); A61K 45/00 (2006.01); A61K 49/00 (2006.01); G01N 33/50 (2006.01)

CPC (source: EP)

A61K 31/00 (2013.01); A61K 31/277 (2013.01); A61K 31/341 (2013.01); A61K 31/4174 (2013.01); A61K 31/4422 (2013.01); A61K 31/4439 (2013.01); A61K 31/444 (2013.01); A61K 31/451 (2013.01); A61K 31/522 (2013.01); A61K 31/554 (2013.01); A61K 31/585 (2013.01); A61P 11/00 (2017.12); A61P 17/00 (2017.12); G01N 33/5008 (2013.01)

Citation (search report)

  • [XY] US 5202130 A 19930413 - GRANT ANHALT [US], et al
  • [X] DD 297062 A5 19920102 - TKS OPTIMUM GMBH [DD]
  • [Y] WO 9102497 A1 19910307 - BETH ISRAEL HOSPITAL [US]
  • [X] EVANS CH ET AL.: "Inhibition, by lanthanides, of neutral proteinases secreted by human rheumatoid synovium", EUR.J.BIOCHEM., vol. 151, 1985, pages 29 - 32, XP002098132
  • [DX] J.INVESTIG.DERMATOL., vol. 93, no. 3, 1989, pages 322 - 326, XP002098133
  • [Y] GANGAROSA L P ET AL: "CONDUCTIVITY OF DRUGS USED FOR IONTOPHORESIS", JOURNAL OF PHARMACEUTICAL SCIENCES, vol. 67, no. 10, October 1978 (1978-10-01), pages 1439 - 1443, XP002055803
  • See references of WO 9527510A1

Designated contracting state (EPC)

AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE

DOCDB simple family (publication)

WO 9527510 A1 19951019; AU 2385795 A 19951030; EP 0757558 A1 19970212; EP 0757558 A4 19990616; EP 0937460 A2 19990825; EP 0937460 A3 20000405; JP H10500669 A 19980120

DOCDB simple family (application)

US 9504677 W 19950411; AU 2385795 A 19950411; EP 95917009 A 19950411; EP 99201333 A 19950411; JP 52654195 A 19950411