EP 0759919 B1 19981111 - AZOLIDINEDIONES AS ANTIHYPERGLYCEMIC AGENTS
Title (en)
AZOLIDINEDIONES AS ANTIHYPERGLYCEMIC AGENTS
Title (de)
AZOLIDINDION-DERIVATE UND IHRE ANWENDUNG ALS ANTIHYPERGLYKÄMIKA
Title (fr)
AZOLIDINEDIONES UTILES COMME AGENTS ANTIHYPERGLYCEMIQUES
Publication
Application
Priority
- US 9504631 W 19950413
- US 24573494 A 19940518
Abstract (en)
[origin: US5468762A] This invention relates to compounds which have oral antihyperglycemic activity of the formula: <IMAGE> I wherein: R1 is C1-C6 alkyl, C3-C8 cycloalkyl, thienyl, furyl, pyridyl, <IMAGE> R2 is hydrogen or C1-C6 alkyl; X os O or S; n is 0, 1, or 2; A is <IMAGE> <IMAGE> <IMAGE> or <IMAGE> Y is O or S; Z is N or CH when Y is O and Z is CH when Y is S; or a pharmaceutically acceptable salt thereof.
[origin: US5468762A] This invention relates to compounds which have oral antihyperglycemic activity of the formula: <IMAGE> I wherein: R1 is C1-C6 alkyl, C3-C8 cycloalkyl, thienyl, furyl, pyridyl, <IMAGE> R2 is hydrogen or C1-C6 alkyl; X os O or S; n is 0, 1, or 2; A is <IMAGE> <IMAGE> <IMAGE> or <IMAGE> Y is O or S; Z is N or CH when Y is O and Z is CH when Y is S; or a pharmaceutically acceptable salt thereof.
IPC 1-7
C07D 413/12; A61K 31/41; C07D 263/32; C07D 413/14; C07D 417/12; A61K 31/425
IPC 8 full level
C07D 277/20 (2006.01); A61K 31/42 (2006.01); A61K 31/421 (2006.01); A61K 31/425 (2006.01); A61K 31/426 (2006.01); A61P 3/08 (2006.01); C07D 263/44 (2006.01); C07D 413/12 (2006.01); C07D 413/14 (2006.01); C07D 417/12 (2006.01); C07D 417/14 (2006.01)
CPC (source: EP KR US)
A61P 3/08 (2017.12 - EP); A61P 3/10 (2017.12 - EP); C07D 263/44 (2013.01 - EP US); C07D 413/12 (2013.01 - EP KR US); C07D 413/14 (2013.01 - EP KR US); C07D 417/12 (2013.01 - EP KR US); C07D 417/14 (2013.01 - KR)
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IE IT LI LU NL PT SE
DOCDB simple family (publication)
US 5468762 A 19951121; AT E173256 T1 19981115; AU 2384295 A 19951205; AU 684357 B2 19971211; CA 2190015 A1 19951123; CN 1152312 A 19970618; DE 69505968 D1 19981217; DE 69505968 T2 19990512; DK 0759919 T3 19990726; EP 0759919 A1 19970305; EP 0759919 B1 19981111; ES 2124545 T3 19990201; GR 3029355 T3 19990528; HU 9603185 D0 19970128; HU T76823 A 19971128; JP H10500133 A 19980106; KR 970703340 A 19970703; NZ 284654 A 19981223; TW 328089 B 19980311; US 5510360 A 19960423; WO 9531454 A1 19951123; ZA 953981 B 19961118
DOCDB simple family (application)
US 24573494 A 19940518; AT 95916989 T 19950413; AU 2384295 A 19950413; CA 2190015 A 19950413; CN 95194037 A 19950413; DE 69505968 T 19950413; DK 95916989 T 19950413; EP 95916989 A 19950413; ES 95916989 T 19950413; GR 990400442 T 19990210; HU 9603185 A 19950413; JP 52964495 A 19950413; KR 19960706490 A 19961116; NZ 28465495 A 19950413; TW 84104226 A 19950428; US 42111195 A 19950413; US 9504631 W 19950413; ZA 953981 A 19950516