EP 0759925 A1 19970305 - ADENOSINE DERIVATIVES
Title (en)
ADENOSINE DERIVATIVES
Title (de)
ADENOSINE-DERIVATE
Title (fr)
DERIVES ADENOSINE
Publication
Application
Priority
- GB 9409324 A 19940510
- GB 9416693 A 19940818
- US 9505802 W 19950509
- US 24991494 A 19940526
Abstract (en)
[origin: WO9530683A1] Compounds of formula (I), wherein R1 is one of a number of significances, including cycloalkyl and hydroxycycloalkyl; R2 is hydrogen, (C1-4)alkyl, amino, (C3-5)cycloalkyl or halogen with an atomic number of 9 to 35, and R3 is (C1-4)alkyl, are useful as analgesic agents. Compounds of formula (I) wherein R1 is hydroxy alkyl are new. The compounds of formula (I) may be produced by alkylation in the 2' position in the presence of tetrabutylammonium hydrogen sulfate and a non-polar solvent.
IPC 1-7
IPC 8 full level
C07H 19/167 (2006.01); A61K 31/70 (2006.01); A61K 31/7042 (2006.01); A61K 31/7052 (2006.01); A61K 31/7076 (2006.01); A61P 25/04 (2006.01); C07H 19/16 (2006.01)
CPC (source: EP)
A61P 25/04 (2017.12); C07H 19/16 (2013.01)
Citation (search report)
See references of WO 9530683A1
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IE IT LI LU NL PT SE
DOCDB simple family (publication)
WO 9530683 A1 19951116; AU 2546195 A 19951129; BR 9507683 A 19970923; CA 2186847 A1 19951116; CN 1147815 A 19970416; CZ 327896 A3 19970312; EP 0759925 A1 19970305; FI 964468 A0 19961106; FI 964468 A 19961106; HU 9603105 D0 19970128; HU T75338 A 19970528; JP H09512823 A 19971222; NO 964735 D0 19961108; NO 964735 L 19970110; PL 316985 A1 19970303; SK 146096 A3 19970709
DOCDB simple family (application)
US 9505802 W 19950509; AU 2546195 A 19950509; BR 9507683 A 19950509; CA 2186847 A 19950509; CN 95192979 A 19950509; CZ 327896 A 19950509; EP 95919777 A 19950509; FI 964468 A 19961106; HU 9603105 A 19950509; JP 52918595 A 19950509; NO 964735 A 19961108; PL 31698595 A 19950509; SK 146096 A 19950509