Global Patent Index - EP 0759976 A4

EP 0759976 A4 20010207 - THE ISOLATION AND PRODUCTION OF CATALYTIC ANTIBODIES USING PHAGE TECHNOLOGY

Title (en)

THE ISOLATION AND PRODUCTION OF CATALYTIC ANTIBODIES USING PHAGE TECHNOLOGY

Title (de)

DIE ISOLIERUNG UND HERSTELLUNG VON KATALYTISCHEN ANTIKÖRPERN MITTELS PHAGENTECHNOLOGIE

Title (fr)

ISOLEMENT ET PRODUCTION D'ANTICORPS CATALYTIQUES PAR UNE TECHNOLOGIE FAISANT APPEL A DES PHAGES

Publication

EP 0759976 A4 20010207 (EN)

Application

EP 94919078 A 19940330

Priority

US 9403420 W 19940330

Abstract (en)

[origin: WO9527045A1] Disclosed and claimed are methods for producing catalytic antibodies, including human catalytic antibodies, from bacteriophage. The methods require the cloning, selection, screening, and isolation of catalytic antibodies. Also disclosed and claimed are the products themselves, the catalytic antibodies, made from the phage technology. In addition, catalytic antibodies produced from the phage technology and useful in prodrug activation are disclosed and claimed. And finally, the invention also understands the production of catalytic antibodies to phosphonates.

IPC 1-7

C12N 9/00; C07K 16/00; A61K 38/43

IPC 8 full level

A61K 39/395 (2006.01); A61K 45/00 (2006.01); A61K 48/00 (2006.01); A61P 43/00 (2006.01); C07K 16/00 (2006.01); C07K 16/44 (2006.01); C12N 9/00 (2006.01); C12N 15/09 (2006.01); C12N 15/10 (2006.01); C40B 40/02 (2006.01); G01N 33/531 (2006.01); A61K 38/00 (2006.01); C12R 1/19 (2006.01)

CPC (source: EP)

A61P 43/00 (2017.12); C07K 16/00 (2013.01); C07K 16/44 (2013.01); C12N 9/0002 (2013.01); C12N 15/1037 (2013.01); C12N 15/1093 (2013.01); C40B 40/02 (2013.01); A61K 38/00 (2013.01); C07K 2319/00 (2013.01)

Citation (search report)

  • [X] WO 9014430 A1 19901129 - SCRIPPS CLINIC RES [US], et al
  • [X] US 5258289 A 19931102 - DAVIS CLAUDE G [US], et al
  • [A] WO 9312232 A1 19930624 - DANA FARBER CANCER INST INC [US], et al
  • [A] MCCAFFERTY J ET AL: "SELECTION AND RAPID PURIFICATION OF MURINE ANTIBODY FRAGMENTS THAT BIND A TRANSITION-STATE ANALOG BY PHAGE DISPLAY", APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY,US,CLIFTON, NJ, vol. 47, 1994, pages 157 - 173, XP002913520, ISSN: 0273-2289
  • See references of WO 9527045A1

Designated contracting state (EPC)

AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE

DOCDB simple family (publication)

WO 9527045 A1 19951012; AU 695406 B2 19980813; AU 7014194 A 19951023; EP 0759976 A1 19970305; EP 0759976 A4 20010207; JP H10507341 A 19980721

DOCDB simple family (application)

US 9403420 W 19940330; AU 7014194 A 19940330; EP 94919078 A 19940330; JP 52562295 A 19940330