EP 0759984 A1 19970305 - MODULATOR OF TNF/NGF SUPERFAMILY RECEPTORS AND SOLUBLE OLIGOMERIC TNF/NGF SUPERFAMILY RECEPTORS
Title (en)
MODULATOR OF TNF/NGF SUPERFAMILY RECEPTORS AND SOLUBLE OLIGOMERIC TNF/NGF SUPERFAMILY RECEPTORS
Title (de)
MODULATOREN DER GENSUPERFAMILIE DER TNF/NGF-REZEPTOREN UND LÖSLICHE, OLIGOMERE REZEPTOREN DER TNF/NGF-SUPERFAMILIE
Title (fr)
MODULATEUR DE RECEPTEURS DE LA SUPER-FAMILLE TNF/NGF ET RECEPTEURS OLIGOMERES SOLUBLES DE LA SUPER-FAMILLE TNF/NGF
Publication
Application
Priority
- IL 10963294 A 19940511
- IL 11112594 A 19941002
- US 9505854 W 19950511
Abstract (en)
[origin: WO9531544A1] The present invention generally concerns novel proteins which bind to the intracellular domains of the p55 and p75 TNF-Rs and the Fas-R, which are capable of modulating the function of the p55 and p75 TNF-Rs and the Fas-R, and the DNA sequences which encode them. The present invention also concerns new soluble oligomeric TNF-Rs, oligomeric Fas-Rs and oligomeric receptors having a mixture of TNF-Rs and Fas-Rs. In addition, the present invention concerns methods of preparation and uses of all of the aforementioned.
IPC 1-7
C12N 15/12; C12N 15/62; C12N 15/67; C12N 1/19; C12N 1/21; C12N 5/10; A61K 38/16; A61K 39/395; A61K 48/00; C07K 14/435; C07K 14/715
IPC 8 full level
C12N 15/62 (2006.01); G01N 33/566 (2006.01); A61K 31/70 (2006.01); A61K 35/76 (2015.01); A61K 38/00 (2006.01); A61K 38/16 (2006.01); A61K 38/20 (2006.01); A61K 39/395 (2006.01); A61K 48/00 (2006.01); A61P 35/00 (2006.01); C07H 21/04 (2006.01); C07K 14/435 (2006.01); C07K 14/47 (2006.01); C07K 14/48 (2006.01); C07K 14/525 (2006.01); C07K 14/705 (2006.01); C07K 14/715 (2006.01); C12N 1/19 (2006.01); C12N 1/21 (2006.01); C12N 5/10 (2006.01); C12N 15/09 (2006.01); C12N 15/12 (2006.01); C12N 15/67 (2006.01); C12P 21/02 (2006.01); C12Q 1/68 (2018.01); C12R 1/19 (2006.01); C12R 1/645 (2006.01); C12R 1/91 (2006.01)
CPC (source: EP KR)
A61K 38/16 (2013.01 - KR); A61P 35/00 (2017.12 - EP); C07K 14/435 (2013.01 - KR); C07K 14/47 (2013.01 - EP); C07K 14/7151 (2013.01 - EP); C12N 15/11 (2013.01 - KR); C12N 15/67 (2013.01 - KR); A61K 38/00 (2013.01 - EP); C07K 2319/00 (2013.01 - EP)
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE
Designated extension state (EPC)
LT LV SI
DOCDB simple family (publication)
WO 9531544 A1 19951123; AU 2546995 A 19951205; AU 703919 B2 19990401; CA 2189983 A1 19951123; CN 1152937 A 19970625; CN 1173033 C 20041027; CN 1329512 C 20070801; CN 1616661 A 20050518; EP 0759984 A1 19970305; EP 0759984 A4 20020626; FI 964509 A0 19961108; FI 964509 A 19970109; IL 111125 A0 19941229; JP 3966387 B2 20070829; JP H10500568 A 19980120; KR 100404737 B1 20040503; KR 970703419 A 19970703; NO 321514 B1 20060515; NO 964741 D0 19961108; NO 964741 L 19970109
DOCDB simple family (application)
US 9505854 W 19950511; AU 2546995 A 19950511; CA 2189983 A 19950511; CN 200410074845 A 19950511; CN 95194095 A 19950511; EP 95919787 A 19950511; FI 964509 A 19961108; IL 11112594 A 19941002; JP 52974895 A 19950511; KR 19960706405 A 19961111; NO 964741 A 19961108