EP 0760666 A1 19970312 - USE OF OLIGONUCLEOTIDE PHOSPHOROTHIOATE FOR DEPLETING COMPLEMENT AND FOR REDUCING BLOOD PRESSURE
Title (en)
USE OF OLIGONUCLEOTIDE PHOSPHOROTHIOATE FOR DEPLETING COMPLEMENT AND FOR REDUCING BLOOD PRESSURE
Title (de)
VERWENDUNG EINES OLIGONUKLEOTID-PHOSPHOROTIOATES ZUR KOMPLEMENTDEPLETION UND ZUR SENKUNG DES BLUTDRUCKS
Title (fr)
UTILISATION DE PHOSPHOROTHIOATE OLIGONUCLEOTIDIQUE POUR LA DEPLETION DU COMPLEMENT ET LA REDUCTION DE LA PRESSION SANGUINE
Publication
Application
Priority
- US 9506161 W 19950519
- US 25085394 A 19940527
Abstract (en)
[origin: WO9532719A1] Disclosed are methods of reducing the blood pressure, stimulating vasodilation, and depleting complement, in a primate. These methods involve administering an oligonucleotide to the primate, and then measuring the decrease in blood pressure or complement activity. The oligonucleotide being administered is 2 to 50 nucleotides in length and has at least one phosphorothioate internucleotide linkage.
IPC 1-7
IPC 8 full level
C07H 21/04 (2006.01); A61K 31/70 (2006.01); A61K 31/7088 (2006.01); A61P 9/12 (2006.01); A61P 37/06 (2006.01)
CPC (source: EP)
A61K 31/70 (2013.01); A61P 9/12 (2017.12); A61P 37/06 (2017.12)
Citation (search report)
See references of WO 9532719A1
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9532719 A1 19951207; AU 2591495 A 19951221; CA 2191192 A1 19951207; EP 0760666 A1 19970312; JP H10501224 A 19980203
DOCDB simple family (application)
US 9506161 W 19950519; AU 2591495 A 19950519; CA 2191192 A 19950519; EP 95920471 A 19950519; JP 50092496 A 19950519