EP 0760815 A1 19970312 - PROCESSES FOR PREPARING 1-BUTYL-2-¬2'-(2H-TETRAZOL-5-YL)-BIPHENYL-4-YLMETHYL -1H-INDOLE-3-CARBOXYLIC ACID
Title (en)
PROCESSES FOR PREPARING 1-BUTYL-2-¬2'-(2H-TETRAZOL-5-YL)-BIPHENYL-4-YLMETHYL -1H-INDOLE-3-CARBOXYLIC ACID
Title (de)
VERFAHREN ZUR HERSTELLUNG VON 1-BUTYL-1-[2'-(2H-TETRAZOL-5-YL)BIPHENYL-4-YLMETHYL-1H-INDOL-3-CARBONSAÜRE
Title (fr)
PROCEDE DE PREPARATION DE L'ACIDE 1-BUTYL-2-¬2'-(2H-TETRAZOL-5-YL)BIPHENYL-4-YLMETHYL -1H-INDOLE-3-CARBOXYLIQUE
Publication
Application
Priority
- US 9506432 W 19950526
- US 25039794 A 19940527
Abstract (en)
[origin: US5412102A] The present invention relates to processes for preparing 1-butyl-2-[2'-(2H-tetrazol-5-yl)biphenyl-4-ylmethyl]-1H-indole-3-carboxylic acid and to intermediates useful in such processes. The present invention also relates to a process for deprotecting compounds containing a protected 2H-tetrazolyl group, which process comprises reacting a the protected compound with a Lewis acid in the presence of a thiol.
IPC 1-7
IPC 8 full level
A61K 31/41 (2006.01); A61P 43/00 (2006.01); C07D 257/04 (2006.01); C07D 403/10 (2006.01)
CPC (source: EP US)
A61P 43/00 (2017.12 - EP); C07D 403/10 (2013.01 - EP US)
Citation (search report)
See references of WO 9532962A1
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
US 5412102 A 19950502; AU 2643995 A 19951221; BR 9507771 A 19970819; CA 2191576 A1 19951207; CN 1070193 C 20010829; CN 1149293 A 19970507; EP 0760815 A1 19970312; IL 113876 A0 19950831; IL 113876 A 20010826; JP H10501230 A 19980203; US 5446121 A 19950829; US 5527918 A 19960618; WO 9532962 A1 19951207; ZA 954306 B 19961126
DOCDB simple family (application)
US 25039794 A 19940527; AU 2643995 A 19950526; BR 9507771 A 19950526; CA 2191576 A 19950526; CN 95193255 A 19950526; EP 95921335 A 19950526; IL 11387695 A 19950526; JP 50098296 A 19950526; US 37367795 A 19950117; US 44004095 A 19950512; US 9506432 W 19950526; ZA 954306 A 19950526