EP 0763022 A1 19970319 - PHENOXYALKYL SUBSTITUTED PIPERIDINES, PYRROLIDINES, MORPHOLINES AND THIOMORPHOLINES AS CALCIUM CHANNEL ANTAGONISTS
Title (en)
PHENOXYALKYL SUBSTITUTED PIPERIDINES, PYRROLIDINES, MORPHOLINES AND THIOMORPHOLINES AS CALCIUM CHANNEL ANTAGONISTS
Title (de)
PHENOXYALKYL SUBSTITUIERTE PIPERIDINE, PYRROLIDINE, MORPHOLINE UND THIOMORPHOLINE ALS CALCIUM KANALANTAGONISTEN
Title (fr)
PIPERIDINES, PYRROLIDINES, MORPHOLINES ET THIOMORPHOLINES A SUBSTITUTION PHENOXYALCOYLE, EN TANT QU'ANTAGONISTES DES CANAUX A CALCIQUES
Publication
Application
Priority
- EP 9502003 W 19950524
- GB 9411045 A 19940602
Abstract (en)
[origin: WO9533723A1] Compounds of formula (I), in which W is -(CH2)4, (CH2)5, -(CH2)2O(CH2)2 or -(CH2)2S(CH2)2 n is 0 to 6; m is 0 to 3; A is a bond, -CH=CH-, -CC-, oxygen, sulphur or NR<1>; R<1> is hydrogen, C1-8alkyl or phenyl C1-4alkyl; and Ar is a group (a) where X is a bond, O, CH2, CO or OCH2 and Hal is fluoro or chloro; and salts thereof are calcium channel antagonists with activity in neurons and are useful in the treatment of conditions such as ischaemic stroke.
IPC 1-7
IPC 8 full level
C07D 279/12 (2006.01); A61K 31/42 (2006.01); A61K 31/445 (2006.01); A61K 31/535 (2006.01); A61K 31/5375 (2006.01); A61P 3/00 (2006.01); A61P 3/14 (2006.01); A61P 9/00 (2006.01); A61P 9/08 (2006.01); A61P 9/10 (2006.01); A61P 25/00 (2006.01); A61P 25/04 (2006.01); A61P 25/08 (2006.01); A61P 25/28 (2006.01); A61P 25/30 (2006.01); C07D 211/22 (2006.01); C07D 265/30 (2006.01)
CPC (source: EP)
A61P 3/00 (2017.12); A61P 3/14 (2017.12); A61P 9/00 (2017.12); A61P 9/08 (2017.12); A61P 9/10 (2017.12); A61P 25/00 (2017.12); A61P 25/04 (2017.12); A61P 25/08 (2017.12); A61P 25/28 (2017.12); A61P 25/30 (2017.12); C07D 211/22 (2013.01)
Citation (search report)
See references of WO 9533723A1
Designated contracting state (EPC)
BE CH DE FR GB IT LI NL
DOCDB simple family (publication)
WO 9533723 A1 19951214; EP 0763022 A1 19970319; GB 9411045 D0 19940720; JP H10500698 A 19980120
DOCDB simple family (application)
EP 9502003 W 19950524; EP 95921759 A 19950524; GB 9411045 A 19940602; JP 50029095 A 19950524