EP 0764153 A1 19970326 - SUBSTITUTED PYRAZOLES HAVING CORTICOTROPIN-RELEASING FACTOR (CRF) ANTAGONIST ACTIVITY
Title (en)
SUBSTITUTED PYRAZOLES HAVING CORTICOTROPIN-RELEASING FACTOR (CRF) ANTAGONIST ACTIVITY
Title (de)
SUBSTITUIERTE PYRAZOLE MIT "CORTICOTROPIN-RELEASING FACTOR"-(CRF) ANTAGONISTISCHER AKTIVITÄT
Title (fr)
PYRAZOLES SUBSTITUES AYANT UNE ACTIVITE ANTAGONISTE DU FACTEUR LIBERANT LA CORTICOTROPINE (FLC)
Publication
Application
Priority
- IB 9500318 W 19950504
- US 25482094 A 19940606
Abstract (en)
[origin: WO9533727A1] The compounds of formula (I) wherein A, R1, R3, X1, Y and Z are as defined herein, have corticotropin-releasing factor (CRF) antagonist activity. They are useful in the treatment of illnesses induced by CRF, such as stress and anxiety related disorders.
IPC 1-7
IPC 8 full level
A61K 31/415 (2006.01); A61K 31/47 (2006.01); A61P 25/20 (2006.01); A61P 29/00 (2006.01); A61P 43/00 (2006.01); C07D 231/12 (2006.01); C07D 231/14 (2006.01); C07D 231/18 (2006.01); C07D 401/06 (2006.01)
CPC (source: EP KR US)
A61K 31/415 (2013.01 - KR); A61P 25/20 (2017.12 - EP); A61P 29/00 (2017.12 - EP); A61P 43/00 (2017.12 - EP); C07D 231/12 (2013.01 - EP KR US); C07D 231/14 (2013.01 - EP US); C07D 231/18 (2013.01 - EP KR US); C07D 401/06 (2013.01 - EP US)
Citation (search report)
See references of WO 9533727A1
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IE IT LI LU NL PT SE
DOCDB simple family (publication)
WO 9533727 A1 19951214; AU 2265495 A 19960104; CA 2192208 A1 19951214; CA 2192208 C 20020910; CN 1149870 A 19970514; EP 0764153 A1 19970326; FI 964893 A0 19961205; FI 964893 A 19961205; IL 113911 A0 19950831; JP 3291299 B2 20020610; JP H09506632 A 19970630; KR 100263429 B1 20000801; KR 970703332 A 19970703; NO 965209 D0 19961205; NO 965209 L 19961205; NZ 284143 A 19990128; US 5968944 A 19991019; ZA 954598 B 19961205
DOCDB simple family (application)
IB 9500318 W 19950504; AU 2265495 A 19950504; CA 2192208 A 19950504; CN 95193419 A 19950504; EP 95915969 A 19950504; FI 964893 A 19961205; IL 11391195 A 19950529; JP 52310795 A 19950504; KR 19960706938 A 19961205; NO 965209 A 19961205; NZ 28414395 A 19950504; US 75064996 A 19961203; ZA 954598 A 19950605