EP 0764272 B1 20010103 - PTPalpha detection in tumour diagnosis and prognosis
Title (en)
PTPalpha detection in tumour diagnosis and prognosis
Title (de)
PTPalpha-Bestimmung in der Tumordiagnose und -Prognose
Title (fr)
Détection de PTPalpha dans le diagnostic et pronostic de tumeurs
Publication
Application
Priority
- EP 9502166 W 19950606
- GB 9411671 A 19940610
Abstract (en)
[origin: WO9534818A1] It has been found that the level of protein tyrosine phosphatase alpha (PTP alpha ) expression is increased in significant numbers of tumors and that PTP alpha can be used as a marker for the diagnosis or prognosis of cancers. Accordingly, the invention provides a method for diagnosis or prognosis of a cancer, which method comprises detection of PTP alpha or PTP alpha nucleic acid. In general, the level of PTP alpha or PTP alpha nucleic acid in a first biological sample derived from tissue suspected of being neoplastic or potentially neoplastic is compared with the level in a second biological sample derived from normal tissue.
[origin: WO9534818A1] It has been found that the level of protein tyrosine phosphatase alpha (PTP alpha ) expression is increased in significant numbers of tumors and that PTP alpha can be used as a marker for the diagnosis or prognosis of cancers. Accordingly, the invention provides a method for diagnosis or prognosis of a cancer, which method comprises detection of PTP alpha or PTP alpha nucleic acid. In general, the level of PTP alpha or PTP alpha nucleic acid in a first biological sample derived from tissue suspected of being neoplastic or potentially neoplastic is compared with the level in a second biological sample derived from normal tissue.
IPC 1-7
IPC 8 full level
G01N 33/574 (2006.01)
CPC (source: EP US)
G01N 33/57446 (2013.01 - EP US); G01N 2474/20 (2021.08 - EP US)
Citation (examination)
SCHUH ET AL.: "Obligatory wounding requirement for tumorigenesis in v-jun transgenic mice", NATURE, vol. 346, 23 August 1990 (1990-08-23), pages 756 - 760
Designated contracting state (EPC)
AT CH DE FR GB IT LI
DOCDB simple family (publication)
WO 9534818 A1 19951221; AT E198513 T1 20010115; AU 2738195 A 19960105; DE 69519796 D1 20010208; DE 69519796 T2 20010419; EP 0764272 A1 19970326; EP 0764272 B1 20010103; GB 9411671 D0 19940803; US 5888746 A 19990330
DOCDB simple family (application)
EP 9502166 W 19950606; AT 95922516 T 19950606; AU 2738195 A 19950606; DE 69519796 T 19950606; EP 95922516 A 19950606; GB 9411671 A 19940610; US 75035297 A 19970310