EP 0767655 A4 19980916 - METHODS OF TREATING HYPERTENSION AND OF IMPROVING IMPAIRED RENAL FUNCTION
Title (en)
METHODS OF TREATING HYPERTENSION AND OF IMPROVING IMPAIRED RENAL FUNCTION
Title (de)
VERFAHREN ZUR BEHANDLUNG VON HYPERTONIE UND ZUM VERBESSERN EINER EINGESCHRÄNKTEN NIERENFUNKTION
Title (fr)
PROCEDES POUR TRAITER L'HYPERTENSION ET POUR AMELIORER LES INSUFFISANCES DE LA FONCTION RENALE
Publication
Application
Priority
- US 9507243 W 19950609
- US 25786594 A 19940610
- US 25786694 A 19940610
Abstract (en)
[origin: WO9534288A1] A method of treating hypertension and related symptoms thereof is described. A suspension of small, unilamellar vesicles composed primarily of phospholipids similar in nature to those of egg phosphatidylcholine is administered parenterally to a subject in need of such treatment repeatedly and over an extended period of time of at least several days, until a significant drop in blood pressure is observed. A method of improving renal function is also disclosed. In the treatment method, a suspension of liposomes is administered parenterally to a subject in need of such improvement repeatedly and over an extended period of time of at least several days, until a significant improvement in renal function is observed, as evidenced by an improvement in glomerular filtration rate characterized by a drop in plasma creatinine concentration of at least 10 percent.
IPC 1-7
IPC 8 full level
A61K 9/127 (2006.01)
CPC (source: EP)
A61K 9/127 (2013.01); A61K 31/685 (2013.01)
Citation (search report)
- [X] EP 0234919 A2 19870902 - HADASSAH MED ORG [IL]
- [X] EP 0461559 A2 19911218 - BRAUN MELSUNGEN AG [DE]
- See references of WO 9534288A1
Designated contracting state (EPC)
BE CH DE ES FR GB IT LI SE
DOCDB simple family (publication)
WO 9534288 A1 19951221; AU 2663895 A 19960105; DE 69533397 D1 20040923; EP 0767655 A1 19970416; EP 0767655 A4 19980916; EP 0767655 B1 20040818; IL 114096 A0 19951031; IL 114096 A 20020210; IL 146735 A 20070920
DOCDB simple family (application)
US 9507243 W 19950609; AU 2663895 A 19950609; DE 69533397 T 19950609; EP 95921621 A 19950609; IL 11409695 A 19950611; IL 14673595 A 19950611