EP 0767773 A1 19970416 - NOVEL ANTITUMOR AND ANTILEUKEMIA SUBSTANCES, PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME
Title (en)
NOVEL ANTITUMOR AND ANTILEUKEMIA SUBSTANCES, PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME
Title (de)
ANTITUMORALE UND ANTILEUKÄMISCHE VERBINDUNGEN, IHRE HERSTELLUNG UND PHARMAZEUTISCHE ZUSAMMENSETZUNGEN, DIE SIE ENTHALTEN
Title (fr)
NOUVELLES SUBSTANCES ANTITUMORALES ET ANTILEUCEMIQUES, LEUR PREPARATION ET LES COMPOSITIONS PHARMACEUTIQUES QUI LES CONTIENNENT
Publication
Application
Priority
- FR 9500814 W 19950620
- FR 9407701 A 19940623
- FR 9500160 A 19950109
Abstract (en)
[origin: WO9600205A1] A 3-(3-hydroxy-4-methoxy-benzyl)-7-methylene-1-vinyl-2,3,3a,4,7,7a-hexa-hydro-indene-4-one of formula (I), and a 3-(3-hydroxy-4-methoxy-benzyl)-4-hydroxy-7-methyl-1-vinyl-indane of formula (II), stereoisomeric forms thereof, a method for obtaining same from the plant Ottelia alismoides, and pharmaceutical compositions containing said substances, are disclosed. The novel substances of formula (I) or (II) have remarkable antitumor and antileukemia properties.
[origin: WO9600205A1] A 3-(3-hydroxy-4-methoxy-benzyl)-7-methylene-1-vinyl-2,3,3a,4,7,7a-hexa- hydro-indene-4-one of formula (I), and a 3-(3-hydroxy-4-methoxy-benzyl)-4-hydroxy-7-methyl-1-vinyl-indane of formula (II), stereoisomeric forms thereof, a method for obtaining same from the plant Ottelia alismoides, and pharmaceutical compositions containing said substances, are disclosed. The novel substances of formula (I) or (II) have remarkable antitumor and antileukemia properties.
IPC 1-7
IPC 8 full level
A61K 36/00 (2006.01); A61K 31/085 (2006.01); A61K 31/12 (2006.01); A61P 1/00 (2006.01); A61P 13/02 (2006.01); A61P 15/00 (2006.01); A61P 17/00 (2006.01); A61P 35/00 (2006.01); A61P 35/02 (2006.01); C07C 41/34 (2006.01); C07C 43/23 (2006.01); C07C 45/78 (2006.01); C07C 45/79 (2006.01); C07C 49/753 (2006.01)
CPC (source: EP US)
A61P 1/00 (2017.12 - EP); A61P 13/02 (2017.12 - EP); A61P 15/00 (2017.12 - EP); A61P 17/00 (2017.12 - EP); A61P 35/00 (2017.12 - EP); A61P 35/02 (2017.12 - EP); C07C 43/23 (2013.01 - EP US); C07C 45/78 (2013.01 - EP US); C07C 49/753 (2013.01 - EP US); C07C 2602/08 (2017.04 - EP US)
Citation (search report)
See references of WO 9600205A1
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IE IT LI LU NL PT SE
DOCDB simple family (publication)
WO 9600205 A1 19960104; AU 2798095 A 19960119; BG 101071 A 19980130; BR 9508364 A 19971104; CA 2192711 A1 19960104; CN 1151154 A 19970604; CZ 380696 A3 19970813; EP 0767773 A1 19970416; FI 965166 A0 19961220; FI 965166 A 19970221; HU 9603541 D0 19970228; HU T76337 A 19970828; JP H10504536 A 19980506; MX 9606534 A 19970329; NO 965504 D0 19961220; NO 965504 L 19961220; PL 317895 A1 19970428; SK 166796 A3 19970604; TW 374764 B 19991121; US 5716994 A 19980210
DOCDB simple family (application)
FR 9500814 W 19950620; AU 2798095 A 19950620; BG 10107196 A 19961220; BR 9508364 A 19950620; CA 2192711 A 19950620; CN 95193728 A 19950620; CZ 380696 A 19950620; EP 95923415 A 19950620; FI 965166 A 19961220; HU 9603541 A 19950620; JP 50286096 A 19950620; MX 9606534 A 19950620; NO 965504 A 19961220; PL 31789595 A 19950620; SK 166796 A 19950620; TW 84106425 A 19950622; US 75083896 A 19961219