EP 0767800 B1 20010328 - HISTIDINE AND HOMOHISTIDINE DERIVATIVES AS INHIBITORS OF PROTEIN FARNESYLTRANSFERASE
Title (en)
HISTIDINE AND HOMOHISTIDINE DERIVATIVES AS INHIBITORS OF PROTEIN FARNESYLTRANSFERASE
Title (de)
HISTIDINE UND HOMOHISTIDINE DERIVATE ZUR VERWENDUNG ALS PROTEIN FARNESYLTRANSFERASE HEMMSTOFFE
Title (fr)
DERIVES D'HISTIDINE ET D'HOMOHISTIDINE EN TANT QU'INHIBITEURS DE FARNESYLTRANSFERASE DE PROTEINES
Publication
Application
Priority
- US 9506660 W 19950530
- US 26836494 A 19940630
Abstract (en)
[origin: US5571792A] Novel inhibitors of protein farnesyltransferase enzyme are described, as well as methods for the preparation and pharmaceutical compositions of the same, which are useful in controlling tissue proliferative diseases, including cancer and restenosis.
IPC 1-7
C07K 5/078; C07K 5/097; C07D 233/64; A61K 38/05; A61K 38/06; A61K 31/415; A61P 35/00
IPC 8 full level
A61K 31/415 (2006.01); A61K 38/55 (2006.01); A61P 9/00 (2006.01); A61P 35/00 (2006.01); A61P 43/00 (2006.01); C07D 233/54 (2006.01); C07D 233/64 (2006.01); C07K 1/02 (2006.01); C07K 1/04 (2006.01); C07K 5/078 (2006.01); C07K 5/097 (2006.01); A61K 38/00 (2006.01)
CPC (source: EP US)
A61P 9/00 (2018.01 - EP); A61P 35/00 (2018.01 - EP); A61P 43/00 (2018.01 - EP); C07D 233/64 (2013.01 - EP US); C07K 5/06139 (2013.01 - EP US); C07K 5/06147 (2013.01 - EP US); A61K 38/00 (2013.01 - EP US)
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9600736 A1 19960111; AT E200085 T1 20010415; AU 2650495 A 19960125; AU 699629 B2 19981210; CA 2190977 A1 19960111; DE 69520499 D1 20010503; DE 69520499 T2 20010726; DK 0767800 T3 20010618; EP 0767800 A1 19970416; EP 0767800 B1 20010328; ES 2158115 T3 20010901; GR 3035936 T3 20010831; HR P950337 A2 19970831; HR P950337 B1 20011231; JP H10502078 A 19980224; MX 9605945 A 19971231; NO 315427 B1 20030901; NO 965604 D0 19961227; NO 965604 L 19970225; NZ 287696 A 19971219; PT 767800 E 20010830; US 5571792 A 19961105; ZA 955411 B 19960205
DOCDB simple family (application)
US 9506660 W 19950530; AT 95921421 T 19950530; AU 2650495 A 19950530; CA 2190977 A 19950530; DE 69520499 T 19950530; DK 95921421 T 19950530; EP 95921421 A 19950530; ES 95921421 T 19950530; GR 20010400790 T 20010525; HR P950337 A 19950614; JP 50315495 A 19950530; MX 9605945 A 19950530; NO 965604 A 19961227; NZ 28769695 A 19950530; PT 95921421 T 19950530; US 26836494 A 19940630; ZA 955411 A 19950629