EP 0769146 A2 19970423 - SCREENING FOR NUC INHIBITORS
Title (en)
SCREENING FOR NUC INHIBITORS
Title (de)
SCREENING VON "NUC" INHIBITOREN
Title (fr)
CRIBLAGE D'INHIBITEURS DE NUC
Publication
Application
Priority
- US 27063594 A 19940701
- US 9508328 W 19950629
Abstract (en)
[origin: WO9601430A2] This invention provides methods for screening for agents useful for treatment of diseases and pathological conditions affected by the level of NUC protein activity. These agents reduce or relieve the repression of PPAR alpha protein and TR protein transcription activation activity by NUC protein. The selected novel or unique agents can be used to treat hyperlipidemia, hypercholesteremia and hyperlipoproteinemia.
IPC 1-7
IPC 8 full level
A61K 38/00 (2006.01); A61K 45/00 (2006.01); A61P 3/06 (2006.01); C07H 21/04 (2006.01); C07K 14/72 (2006.01); C12Q 1/68 (2018.01); G01N 33/15 (2006.01); G01N 33/68 (2006.01); G01N 33/74 (2006.01)
CPC (source: EP)
A61P 3/06 (2017.12); C07K 14/721 (2013.01); C12Q 1/68 (2013.01); G01N 33/68 (2013.01); G01N 33/74 (2013.01); G01N 2500/00 (2013.01)
Citation (search report)
See references of WO 9601430A2
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9601430 A2 19960118; WO 9601430 A3 19961010; AU 2957195 A 19960125; CA 2193685 A1 19960118; EP 0769146 A2 19970423; JP H10502454 A 19980303
DOCDB simple family (application)
US 9508328 W 19950629; AU 2957195 A 19950629; CA 2193685 A 19950629; EP 95925440 A 19950629; JP 50395095 A 19950629