EP 0770086 A4 19980715 - MACROPHAGE MIGRATION INHIBITORY FACTOR-3
Title (en)
MACROPHAGE MIGRATION INHIBITORY FACTOR-3
Title (de)
MAKROPHAGENMIGRATION INHIBIERENDER FAKTOR-3
Title (fr)
FACTEUR-3 INHIBITEUR DE LA MIGRATION DES MACROPHAGES
Publication
Application
Priority
US 9405385 W 19940516
Abstract (en)
[origin: WO9531468A1] The present invention relates to a human MIF-3 and DNA (RNA) encoding such polypeptide. Also provided is a procedure for producing such polypeptide by recombinant techniques and antibodies and antagonists/inhibitors against such polypeptide. Also provided are methods of using the polypeptide therapeutically for treating cancer, infections, acceleration of wound healing, stimulating the immune system, as an anti-inflammatory. Methods of using antibodies and antagonists/inhibitors for therapeutic purposes, is also disclosed, for example, for treating lethal endotoxaemia, ocular inflammation and diagnosing immune diseases.
IPC 1-7
C07H 17/00; C12N 15/00; C12N 1/20; C12P 21/06; A61K 38/00; C07K 1/00; C07K 14/00; C07K 17/00
IPC 8 full level
G01N 33/53 (2006.01); A61K 35/76 (2006.01); A61K 38/00 (2006.01); A61K 39/395 (2006.01); A61K 48/00 (2006.01); A61P 31/12 (2006.01); A61P 35/00 (2006.01); A61P 37/04 (2006.01); C07H 21/04 (2006.01); C07K 14/47 (2006.01); C07K 14/52 (2006.01); C07K 16/18 (2006.01); C12N 1/21 (2006.01); C12N 15/09 (2006.01); C12P 21/02 (2006.01); C12P 21/08 (2006.01); C12R 1/19 (2006.01)
CPC (source: EP)
A61P 31/12 (2017.12); A61P 35/00 (2017.12); A61P 37/04 (2017.12); C07K 14/52 (2013.01); A61K 38/00 (2013.01)
Citation (search report)
- [AD] S. HIROSE ET AL.: "Macrophage Migration Inhibitory Factor {MIF} produced by a human T cell hybridoma clone", MICROBIOLOGY AND IMMUNOLOGY, vol. 35, no. 3, 1991, pages 235 - 245, XP000672573
- See references of WO 9531468A1
Designated contracting state (EPC)
BE CH DE FR GB IT LI NL
DOCDB simple family (publication)
WO 9531468 A1 19951123; AU 7394294 A 19951205; EP 0770086 A1 19970502; EP 0770086 A4 19980715; JP H10500301 A 19980113
DOCDB simple family (application)
US 9405385 W 19940516; AU 7394294 A 19940516; EP 94923875 A 19940516; JP 52959395 A 19940516