EP 0772597 B1 20011212 - 3,4-SUBSTITUTED PYRAZOLES FOR THE TREATMENT OF INFLAMMATION
Title (en)
3,4-SUBSTITUTED PYRAZOLES FOR THE TREATMENT OF INFLAMMATION
Title (de)
3,4-SUBSTITUIERTE PYRAZOLE ZUR BEHANDLUNG VON ENTZÜNDUNGEN
Title (fr)
PYRAZOLES 3,4-SUBSTITUEES DESTINEES AU TRAITEMENT DES INFLAMMATIONS
Publication
Application
Priority
- US 9508788 W 19950720
- US 27829794 A 19940721
Abstract (en)
[origin: US5756530A] A class of pyrazolyl compounds is described for use in treating inflammation and inflammation-related disorders. Compounds of particular interest are defined by Formula II: <IMAGE> (II) wherein R1 is selected from hydrido, alkyl, alkenyl, aralkyl, alkynyl, cyanoalkyl, carboxyalkyl, aminocarbonylalkyl, arylaminocarbonylalkyl, heterocyclicalkyl, and alkoxycarbonylalkyl; wherein R3 is aryl substituted at a substitutable position with halo; wherein R4 is selected from hydrido and haloalkyl; and wherein R5 is selected from alkyl and amino; or a pharmaceutically-acceptable salt or prodrug thereof.\!
IPC 1-7
IPC 8 full level
A61K 31/415 (2006.01); A61K 31/44 (2006.01); A61K 31/4427 (2006.01); A61K 31/47 (2006.01); A61K 31/505 (2006.01); A61P 19/02 (2006.01); A61P 25/04 (2006.01); A61P 29/00 (2006.01); C07D 231/12 (2006.01); C07D 401/04 (2006.01); C07D 401/14 (2006.01); C07D 403/04 (2006.01)
CPC (source: EP US)
A61P 19/02 (2018.01 - EP); A61P 25/04 (2018.01 - EP); A61P 29/00 (2018.01 - EP); C07D 231/12 (2013.01 - EP US)
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IE IT LI LU NL PT SE
DOCDB simple family (publication)
EP 1127878 A1 20010829; AT E210648 T1 20011215; AU 3126795 A 19960222; CA 2195123 A1 19960208; DE 69524600 D1 20020124; DE 69524600 T2 20020718; DK 0772597 T3 20020408; EP 0772597 A1 19970514; EP 0772597 B1 20011212; ES 2169760 T3 20020716; JP 3490716 B2 20040126; JP H10503201 A 19980324; PT 772597 E 20020531; US 5486534 A 19960123; US 5580985 A 19961203; US 5756530 A 19980526; US 6028072 A 20000222; WO 9603385 A1 19960208
DOCDB simple family (application)
EP 01112883 A 19950720; AT 95927154 T 19950720; AU 3126795 A 19950720; CA 2195123 A 19950720; DE 69524600 T 19950720; DK 95927154 T 19950720; EP 95927154 A 19950720; ES 95927154 T 19950720; JP 50578196 A 19950720; PT 95927154 T 19950720; US 27829794 A 19940721; US 53568895 A 19950928; US 72178796 A 19960925; US 77609097 A 19970609; US 9508788 W 19950720