Title (en)

PHENOXYPHENYLACETIC ACID DERIVATIVES

Title (de)

PHENOXYPHENYLESSIGSÄUREDERIVATE

Title (fr)

DERIVES DE L'ACIDE PHENOXYPHENYLACETIQUE

Publication

EP 0774965 A1 19970528 (EN)

Application

EP 95929396 A 19950807

Priority

• US 9509967 W 19950807
• US 28737494 A 19940808
• US 29423294 A 19940822
• US 47317295 A 19950607

Abstract (en)

[origin: WO9604905A1] Phenoxyphenylacetic acids and derivatives of general structural formula (I) have endothelin antagonist activity and are useful in treating cardiovascular disorders, such as hypertension, postischemic renal failure, vasospasm, cerebral and cardiac ischemia, myocardial infarction, endotoxic shock, benign prostatic hyperplasia, inflammatory diseases including Raynaud's disease and asthma.

IPC 1-7

A61K 31/335; C07D 317/54; C07D 317/56; C07D 317/58

IPC 8 full level

A61K 31/357 (2006.01); A61K 31/36 (2006.01); A61P 9/00 (2006.01); A61P 9/08 (2006.01); A61P 9/10 (2006.01); A61P 9/12 (2006.01); A61P 11/00 (2006.01); A61P 13/02 (2006.01); A61P 15/00 (2006.01); C07C 65/24 (2006.01); C07D 317/60 (2006.01); C07D 405/12 (2006.01); C07D 409/12 (2006.01)

CPC (source: EP)

A61P 9/00 (2017.12); A61P 9/08 (2017.12); A61P 9/10 (2017.12); A61P 9/12 (2017.12); A61P 11/00 (2017.12); A61P 13/02 (2017.12); A61P 15/00 (2017.12); C07C 65/24 (2013.01); C07D 317/60 (2013.01); C07D 405/12 (2013.01); C07D 409/12 (2013.01)

Designated contracting state (EPC)

AT BE CH DE DK ES FR GB GR IE IT LI LU NL PT SE

DOCDB simple family (publication)

WO 9604905 A1 19960222; CA 2195758 A1 19960222; EP 0774965 A1 19970528; EP 0774965 A4 19971029; JP H10503779 A 19980407

DOCDB simple family (application)

US 9509967 W 19950807; CA 2195758 A 19950807; EP 95929396 A 19950807; JP 50742596 A 19950807