EP 0776335 A4 19990915 - REGULATABLE ELIMINATION OF GENE EXPRESSION, GENE PRODUCT FUNCTION AND ENGINEERED HOST CELLS
Title (en)
REGULATABLE ELIMINATION OF GENE EXPRESSION, GENE PRODUCT FUNCTION AND ENGINEERED HOST CELLS
Title (de)
REGULIERBARE ELIMINATION DER GENEXPRESSION, GENPRODUKTFUNKTION UND GENTECHNOLOGISCH HERGESTELLTE WIRTSZELLEN
Title (fr)
ELIMINATION MODULABLE D'EXPRESSION GENIQUE, DE FONCTION DE PRODUIT GENIQUE, ET DE CELLULES HOTES OBTENUES PAR GENIE GENETIQUE
Publication
Application
Priority
- US 9510591 W 19950818
- US 29259594 A 19940818
- US 29259694 A 19940818
- US 29259794 A 19940818
Abstract (en)
[origin: WO9606111A1] Materials and methods are disclosed for regulated obstruction of the expression of a target gene or the biological effect of its gene product in genetically engineered cells or organisms containing them. Aspects of the invention are exemplified by recombinant modifications of host cells and their use in vitro and in vivo for the regulatable blockade of expression of a target gene, for interference with the function or effect of a target gene product or for the regulatable elimination of a target gene.
IPC 1-7
IPC 8 full level
A01K 67/027 (2006.01); A61K 48/00 (2006.01); C07K 7/64 (2006.01); C07K 14/715 (2006.01); C07K 14/725 (2006.01); C07K 19/00 (2006.01); C12N 5/10 (2006.01); C12N 15/09 (2006.01); C12N 15/63 (2006.01); C12P 17/18 (2006.01)
CPC (source: EP)
A61K 48/00 (2013.01); C07K 7/645 (2013.01); C07K 14/7051 (2013.01); C07K 14/715 (2013.01); C12N 15/63 (2013.01); C12P 17/188 (2013.01); A01K 2217/05 (2013.01); C07K 2319/00 (2013.01); C07K 2319/03 (2013.01); C07K 2319/035 (2013.01); C07K 2319/09 (2013.01); C07K 2319/20 (2013.01); C07K 2319/42 (2013.01); C07K 2319/43 (2013.01); C07K 2319/71 (2013.01); C07K 2319/715 (2013.01); C07K 2319/81 (2013.01); C07K 2319/90 (2013.01)
Citation (search report)
- [A] EP 0425004 A2 19910502 - AVEVE NV [BE], et al
- [A] WO 9314768 A1 19930805 - UNIV PENNSYLVANIA [US]
- [T] WO 9418317 A1 19940818 - UNIV LELAND STANFORD JUNIOR [US], et al
- [A] ZHAO, J.J. ET AL.: "Generating loss-of-function phenotypes of the fushi tarazu gene with a targeted ribozyme in Drosophila.", NATURE, vol. 365, 30 September 1993 (1993-09-30), pages 448 - 451, XP002108426
- See references of WO 9606111A1
Designated contracting state (EPC)
AT CH DE FR GB LI SE
DOCDB simple family (publication)
WO 9606111 A1 19960229; AU 3409295 A 19960314; CA 2197242 A1 19960229; EP 0776335 A1 19970604; EP 0776335 A4 19990915; JP H10507624 A 19980728
DOCDB simple family (application)
US 9510591 W 19950818; AU 3409295 A 19950818; CA 2197242 A 19950818; EP 95930868 A 19950818; JP 50823895 A 19950818